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A 24-month-old Nigerian girl developed early puberty with no family history, needing treatment her family couldn't afford.

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

Effective PCOS treatments require targeting specific signaling pathways.

Men with Type 2 Diabetes have lower DHT levels, which may affect fertility and lipid profiles.

Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.

Treating early puberty with hormone therapy may increase the risk of polycystic ovary syndrome in adults.

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Resveratrol helps prevent finasteride-induced damage in male rats, improving reproductive function.

Hair graying is influenced by factors like nerves, fat cells, and immune cells, not just hair follicles.

Phthirusa pyrifolia extract may lower testosterone and harm male rat reproduction without damaging the liver or kidneys.

Diagnosing and managing PCOS in teens is hard, but early diagnosis and lifestyle changes are key, and more research is needed for long-term health.

A certain genetic variation is linked to a higher risk of polycystic ovarian syndrome.

Men with early balding should be checked for metabolic syndrome, as there's a link between the two.

Too much male hormone in mothers can negatively affect the sexual behavior of both male and female baby mice.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Hormones control reproduction and are crucial for body balance.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Oestrogens are key for bone growth during puberty in both boys and girls.

The article concludes that better diagnosis and management of Polycystic Ovarian Syndrome are needed to improve women's health and prevent related diseases.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.