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This study found that the pH-sensitive hydrogel HECHA13, containing isoliquiritigenin, effectively inhibited the growth of Propionibacterium acnes and showed promise for transdermal delivery in acne treatment.

This study developed a stable lyophilized finasteride nanosystem for topical delivery and found that it was stable for 90 days and that formulations with 15% trehalose showed favorable characteristics for potential use in treating androgenic alopecia.

This study demonstrated that a new topical treatment using ketotifen-loaded microneedles, designed for prolonged release, significantly reduced inflammatory markers in an animal model of allergic conjunctivitis, suggesting enhanced therapeutic delivery and sustained ocular benefits.

In these two clinical trials, DS-2325a, a KLK5 inhibitor, was found to be generally safe and well tolerated in healthy volunteers, with mild and non-serious adverse events, suggesting its potential for further development as a treatment for Netherton Syndrome.

This study demonstrated that the IVL-DrugFluidic® platform is effective for mass-producing finasteride-loaded polymeric microspheres for long-acting injectables, maintaining stable drug release without an initial burst for a month.

This animal study found that intravenous administration of anionic squarticles, a lipid nanoemulsion, increased survival rates in rats with amitriptyline overdose by mitigating adverse effects and restoring normal blood pressure, highlighting its potential as a detoxifying antidote.

0.1% piroctone olamine in hair tonics effectively treats dandruff.

In this study, oral dienogest combined with ethinylestradiol provided effective contraception with a Pearl Index of approximately 0.2 and improved androgenic symptoms without significant metabolic effects.

This study discusses the use of oral contraceptives as a treatment for hyperandrogenism, showing improvement in hirsutism and acne for many women and possibly providing metabolic benefits with certain formulations.

This case report describes a 34-year-old woman with pituitary stalk interruption syndrome, highlighting the need for long-term follow-up due to potential progression from isolated hormonal deficiencies to pan-hypopituitarism.

This case report describes severe hypothyroidism exacerbated by nephrotic syndrome in a 62-year-old woman, with a diagnosis of membranous nephropathy linked to significant proteinuria.

In this prospective case series, intralesional triamcinolone injections significantly reduced erythema, edema, suppuration, size, and pain in acute hidradenitis suppurativa flares, though the study's small size and design limit the findings.

This article describes SAHA syndrome, which includes symptoms of nodulocystic or severe acne, female pattern hair loss, and hirsutism, but reports no new results.

This article reviews various strategies, primarily developed by the Turin University Pharmaceutical Technology group, for increasing entrapment efficiency of hydrophilic molecules in nanoparticulate systems and reports no clinical results.

This study found that GnRH agonist treatment improved hirsutism scores more than finasteride after six months in women with idiopathic hirsutism, with both treatments causing no menstrual abnormalities or side-effects.

Some birth control pills increase blood clot risk; use them for specific conditions only.

Idiopathic hypoparathyroidism is rare and can be managed with dihydrotachysterol.

In this report, a 47-year-old woman with subclinical hypothyroidism experienced significant symptom relief and normalized TSH levels after six months of individualized homeopathic treatment with Sepia 1M, targeted to her symptom profile.

This study found that ovarian suppression significantly reduced serum testosterone and androstenedione in women with polycystic ovarian syndrome and idiopathic hirsutism, with hair growth rates decreasing more in polycystic ovarian syndrome.

Some drugs can cause serious side effects, like hypoglycemia from mix-ups, skin reactions, or depression, and while penicillamine may help rheumatoid arthritis more than auranofin, it has more severe side effects.

This study observed a strong overall reduction in the use of CPA/EE in the Netherlands, despite similar proportions of users with acne or other hyperandrogenic conditions before and after the referral procedure.

This study observed that proretinal nanoparticles delivered significantly higher concentrations of retinal to the stratum corneum and hair follicles compared to non-particulate forms, potentially improving topical retinoid therapy.

This study found that cyproterone compound is not more effective than oral isotretinoin in treating nodulocystic acne in adult females with SAHA syndrome or cutaneous hyperandrogenism, suggesting isotretinoin may be preferable due to its established effectiveness in reducing acne lesions.

This review describes advanced drug delivery systems for dithranol aimed at overcoming stability issues and skin irritation seen in conventional formulations, highlighting options like nanoparticles and liposomes for improved psoriasis treatment.

This review develops expert-guided recommendations for hidradenitis suppurativa management, highlighting evidence for the effectiveness of antibacterial and anti-tumor necrosis factor therapies, but reports no new clinical trial results.

This case report found that a 48-year-old woman with idiopathic twenty-nail dystrophy experienced significant improvement in nail appearance after six months of treatment with oral Upadacitinib.