TLDR Some birth control pills increase blood clot risk; use them for specific conditions only.
In 2002, the New Zealand Ministry of Health advised women using cyproterone-containing oral contraceptives to consult their health practitioners due to a study indicating an increased risk of venous thromboembolism (VTE). The study, published in the Lancet, found that these contraceptives were associated with a 4-fold increase in VTE risk compared to contraceptives containing levonorgestrel. Following 18 reports of VTE, including 15 cases of pulmonary embolism, associated with cyproterone-containing contraceptives, the Ministry issued prescribing advice to limit their use to conditions like polycystic ovary syndrome, hirsutism, androgenic alopecia, or severe acne. No fatalities were reported.
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January 2012 in “The European Journal of Contraception & Reproductive Health Care” Some birth control pills have a higher risk of blood clots than others.
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December 2009 in “Clinics in Dermatology” Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.
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March 2013 in “The European Journal of Contraception & Reproductive Health Care” The paper suggests that France's suspension of Diane-35 was hasty and could cause treatment issues and unintended pregnancies, recommending a re-evaluation and better patient information.
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June 2015 in “British Journal of Dermatology” Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.
March 2022 in “International journal of pharmaceutical sciences review and research” PCOS is a hormonal issue in women that is usually treated with birth control pills, metformin, and lifestyle changes, with early treatment helping to reduce complications and improve life quality.