1 citations
,
March 2022 in “British Journal of Clinical Pharmacology” In this study, the use of 5-α reductase inhibitors was not associated with an increased risk of anaemia compared to α-blockers in men with benign prostatic hyperplasia.
December 2025 in “International Neurourology Journal” This study examined the dementia risk in patients with benign prostatic hyperplasia using alpha-blockers and 5-alpha reductase inhibitors, finding no significant association between these medications and increased dementia risk compared to no treatment, but noted higher risk probabilities for certain 5ARIs.
September 2025 in “JCEM Case Reports” In this case report, a 46-year-old woman initially diagnosed with 21-hydroxylase deficiency congenital adrenal hyperplasia was later identified as having 3β-HSD2 deficiency after further investigation, highlighting the need for awareness of rarer CAH forms to prevent delayed diagnosis and insufficient treatment.
June 2025 in “Journal of Endocrinological Investigation” This review identifies and discusses various endocrine-related causes of hypertension in children and adolescents, emphasizing the role of genetic predispositions and highlighting the need for systematic diagnostic guidelines and genetic sequencing referrals to improve diagnosis and treatment strategies.
January 2025 in “Current Trends in Pharmacy and Pharmaceutical Chemistry” This review examines recent advancements in analytical techniques used to quantify dutasteride, a medication for enlarged prostate, in various biological samples and its commercial forms, emphasizing methods such as HPTLC, GC-MS, and HPLC.
November 2023 in “International journal of reproduction, contraception, obstetrics and gynecology” This review discusses the hypotheses surrounding the developmental origins of polycystic ovary syndrome, particularly the role of prenatal androgen exposure, and reports no new experimental results.
November 2023 in “Open Repository of the University of Porto (University of Porto)” Pharmacists play a crucial role in patient care and education.
August 2022 in “IntechOpen eBooks” This article reviews congenital adrenal hyperplasia, a group of rare genetic disorders affecting steroid synthesis, and highlights the need for specific therapy and ongoing monitoring, but reports no new clinical findings.
April 2017 in “Turkish Journal of Pediatric Disease” This study found that 20% of children initially diagnosed with premature pubarche were later identified with other conditions like central puberty precox or congenital adrenal hyperplasia during follow-up, emphasizing the importance of ongoing differential diagnosis.
March 2016 in “Korean Journal of Medicine” This study reported that doxazosin may result in gynecomastia after administration but evidence and expert reviews on this are still lacking domestically.
February 2010 in “Journal of The American Academy of Dermatology” This study found that nonobese women with idiopathic hirsutism had significantly lower nitrite/nitrate concentrations and higher fibrinogen levels compared to controls, but similar levels to women with PCOS.
February 2010 in “ePrints Soton (University of Southampton)” This research found that androgen bioactivity plays a role in normal female sexual differentiation, suggesting females develop within a significant androgenic environment, with implications for understanding conditions like congenital adrenal hyperplasia.
December 1997 in “Journal of The European Academy of Dermatology and Venereology” In this study, hormonal abnormalities were detected in all investigated hirsute Saudi women, with elevated major androgens in 85.9% and polycystic ovaries in 59% of cases.
July 1996 in “Trends in Endocrinology and Metabolism” The book is a valuable reference on androgenic disorders for professionals but not suitable for laypeople or medical students.
March 2026 in “Translational Andrology and Urology” The authors concluded that while finasteride 1 mg affects prostate-related pathways, evidence is insufficient to prove clinical benefits for prostate outcomes compared to the established effectiveness of finasteride 5 mg.
September 2025 in “Journal of Cosmetic Dermatology” Single-needle radiofrequency is effective and safe for treating facial sebaceous hyperplasia.
June 2025 in “Molecular Genetics & Genomic Medicine” This study found that among children with 21-hydroxylase deficiency, there is a strong correlation between severe genetic variants and clinical outcomes, but the correlation weakens with milder variants, indicating the limitations of relying solely on NGS for diagnosis.
August 2024 in “Australasian Journal of Dermatology” This study found that finasteride users had a very low rate of psychiatric side effects, with no significant increase in BPH patients and a slight increase in anxiety and depression among AGA patients.
July 2023 in “International Journal of Molecular Sciences” In this study, Trapa bispinosa Roxb. pericarp extract demonstrated inhibitory effects on 5α-reductase activity both in vitro using LNCaP cells and in vivo in a mouse model of benign prostatic hyperplasia, suggesting its potential role in managing the condition.
January 2020 in “Journal of Men s Health” In this study of BPH patients with testosterone deficiency, the combination of TU and dutasteride reduced prostate volume and improved testosterone-related symptoms but was less effective for sexual function compared to TU alone, indicating caution in using dutasteride for those with sexual dysfunction concerns.
March 2016 in “National Repository of Dissertations in Serbia” This study found that dutasteride is more cost-effective compared to finasteride for treating benign prostatic hyperplasia in Montenegro, justifying its funding by the national health insurance fund.
January 2016 in “Archivio italiano di urologia, andrologia” This article reviews treatment-induced sexual dysfunctions related to 5-alpha-reductase inhibitors and reports no new results; it highlights the need to better define and understand this controversial topic.
October 2015 in “Elsevier eBooks” Chewing betel nut may increase the risk of type 2 diabetes, and saw palmetto can improve urinary symptoms in BPH with fewer side effects but may cause bleeding and allergic reactions.
January 2020 in “Química Nova” This study used Density Functional Theory-based computational methods to analyze finasteride's molecular properties, finding that the GGA/PW91 method closely matches experimental data for vibrational frequencies and geometric parameters.
January 2020 in “Archives of urology” This review discusses concerns about persistent side effects of finasteride, such as sexual dysfunction and suicidal ideation, urging the medical community to recognize and address these issues.
February 2010 in “Journal of The American Academy of Dermatology” This review examines microbial production and applications of gluconic acid, focusing on the enzymatic processes involved, and offers no new experimental results.
11 citations
,
June 2020 in “Biomedicines” This study concluded that incorporating the percentage of free PSA and urinary markers improves the accuracy of determining the need for prostate biopsy.
1 citations
,
January 2014 in “Springer eBooks” Adult acne is more common in women, often linked to hormones, and can be harder to treat.
8 citations
,
August 2021 in “Fertility and Sterility” This review discusses the potential risks of ejaculatory dysfunction associated with both medical and surgical treatments for lower urinary tract symptoms due to benign prostatic hyperplasia and their implications for male fertility, but it reports no new clinical results.
5 citations
,
April 2025 in “Journal of the European Academy of Dermatology and Venereology” The EADV Task Force on Hair Diseases reviewed existing literature and clinical experience to propose diagnostic and therapeutic recommendations for managing folliculitis decalvans, highlighting oral antibiotics, glucocorticosteroids, isotretinoin, and various systemic and topical therapies as key options for managing inflammation and preventing further hair loss.