TLDR 5α-reductase inhibitors do not increase anaemia risk compared to α-blockers in men with BPH.
The study examined the risk of anemia in men with benign prostatic hyperplasia (BPH) using 5-α reductase inhibitors (5αRIs) compared to α-blockers, involving 62,380 patients. It found no increased risk of anemia with 5αRIs, with a hazard ratio of 0.95, indicating a slightly lower risk that was not statistically significant. The study's robust methodology, including propensity-score matching and sensitivity analyses, supported the reliability of these findings, providing reassurance about the safety of 5αRIs concerning anemia in this population.
137 citations
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March 2006 in “Cns Drug Reviews” Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
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July 2002 in “BJUI” Finasteride can cause low platelet count in rare cases.
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October 1999 in “Journal of The American Academy of Dermatology” Finasteride effectively reduces hair loss by decreasing androgen levels.
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February 1998 in “The New England Journal of Medicine” Finasteride reduces urinary issues and surgery need in men with enlarged prostates by over 50%.
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October 2004 in “PubMed” Finasteride, especially in a 1mg dose, effectively slows hair loss and improves hair growth in Japanese men with male pattern hair loss.
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June 2001 in “PubMed” Finasteride is effective in growing hair and stopping hair loss in men with mild to moderate alopecia.
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October 1995 in “International Journal of Dermatology” Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
