5 citations
,
October 2017 in “JOGC/Journal of obstetrics and gynaecology Canada” This review discusses the causes and management of hirsutism and suggests improvement can be achieved with a combination of hair removal, suppression of androgen production, and lifestyle changes over 6 to 9 months.
26 citations
,
March 2014 in “Arquivos Brasileiros De Endocrinologia E Metabologia” This review discusses the definition, causes, diagnostic strategies, and treatment options for hirsutism in women without reporting new clinical results, and highlights the impact of the condition on self-esteem.
3 citations
,
August 2019 in “Journal of The American Academy of Dermatology” This report shares the authors' experience using spironolactone for treating acne in a PCOS clinic, but provides no new clinical results.
63 citations
,
August 2022 in “Diagnostics” This review discusses hirsutism in women with PCOS who present with normal androgen levels and highlights diagnostic challenges, reporting no new clinical findings.
19 citations
,
July 2024 in “Journal of Cellular and Molecular Medicine” In this study, women with PCOS who took 12 mg of Astaxanthin daily for 8 weeks showed a reduction in certain inflammatory markers and apoptosis-related genes, suggesting potential benefits for managing PCOS, though effects on symptoms like BMI and hirsutism were not significant.
3 citations
,
July 2011 in “Expert Review of Dermatology” This article reviews the causes and treatments of hirsutism, emphasizing the importance of considering ethnic and cultural norms when interpreting grading systems, and reports no new original findings.
101 citations
,
January 1985 in “British Journal of Dermatology” This article discusses oral spironolactone therapy for female patients with acne, hirsutism, or androgenic alopecia and reports no new clinical results.
January 2023 in “Scholars journal of applied medical sciences” This study found that polycystic ovary syndrome and idiopathic hirsutism are the main causes of hirsutism in the women studied at a gynecology clinic, accounting for about 94% of cases.
November 2022 in “Journal of the Endocrine Society” This case report highlights a rare ovarian steroid cell tumor as the cause of androgen excess in a 36-year-old woman and underscores the importance of thorough preoperative workup to avoid unnecessary surgery.
This review discusses the role of hormonal influences and antiandrogenic treatments in managing hirsutism and other androgenic manifestations in women, highlighting cyproterone acetate as a beneficial option for cosmetically sensitive patients, and reports no new clinical results.
42 citations
,
February 1985 in “Journal of the American Academy of Dermatology” This study reports that once neoplastic causes are excluded, functional hirsutism can be effectively treated with low-dose dexamethasone, oral contraceptives, and spironolactone.
1 citations
,
January 2009 in “Gynecological endocrinology” This article discusses hirsutism, a condition causing excessive hair growth in women, and offers no new clinical results.
43 citations
,
August 2010 in “Expert Opinion on Investigational Drugs” This review explores the potential of selective 11β-HSD1 inhibitors to improve insulin sensitivity in type 2 diabetes, emphasizing the need for more clinical research and reports no new clinical results.
1 citations
,
September 2002 in “European Journal of Endocrinology” This case study reports the clinical features of triple H syndrome in a 25-year-old man, including ACTH deficiency, alopecia universalis, and anterograde amnesia, which were improved with hydrocortisone treatment.
May 2021 in “Boletín latinoamericano y del Caribe de plantas medicinales y aromáticas” This study found that ethanolic extracts of Microsechium helleri showed notable antioxidant, hypoglycemic, and cardioprotective activities, while chloroformic extracts exhibited significant anti-inflammatory effects in experimental models.
November 2021 in “Khyber Medical University Journal” This case report highlights that uncommon ovarian tumors like sclerosal stromal tumors can cause hirsutism and virilization in postmenopausal women and lead to androgen secretion, despite typically being hormonally inactive.
5 citations
,
June 2015 in “International Journal of Women's Dermatology” This article reviews hirsutism from an endocrine perspective and reports no new clinical findings.
1 citations
,
July 2006 in “Reviews in gynaecological and perinatal practice” This review explores various therapeutic options for managing female hirsutism, emphasizing the effectiveness of low-dose finasteride and cyproterone acetate, but it presents no new clinical results.
19 citations
,
October 2019 in “Clinical and Experimental Dermatology” This study found that spironolactone significantly reduced pain, lesion count, and disease severity in patients with hidradenitis suppurativa, as reported in multiple patient cohorts.
50 citations
,
December 2022 in “Food Chemistry Advances” This review discusses diosgenin's potential benefits for several chronic diseases and emphasizes extraction and quantification techniques, but reports no clinical findings.
13 citations
,
August 2020 in “Der Hautarzt” This article discusses hyperandrogenism, including its symptoms, causes, and diagnostic approaches, and reports no new clinical results; it emphasizes the role of interdisciplinary care in treatment.
February 2026 in “Experimental Dermatology” In human hair follicle cultures, this study found that cyclohexyl salicylate, an OR2A4/7 agonist, promoted hair growth by delaying catagen development and expanding epithelial stem cell progeny, suggesting its potential as a non-drug hair loss treatment.
This study found that women with postadolescent acne often exhibit symptoms of hyperandrogenism, such as hirsutism and androgenetic alopecia, but have minimal hormone profile abnormalities.
19 citations
,
August 2018 in “JAMA dermatology” This study found that skin mesenchymal stem cells from hidradenitis suppurativa patients overexpress proinflammatory and anti-inflammatory cytokines, suggesting their potential contribution to the disease's pathogenesis.
January 2025 in “International Journal of Dermatology Sciences” This study found that among women with PCOS, common skin conditions like hirsutism and acne significantly affect quality of life, particularly impacting social and physical domains as measured by the WHOQOL-BREF.
48 citations
,
July 2018 in “Journal of The American Academy of Dermatology” This study observed that treatment with spironolactone significantly improved pain, inflammatory lesion count, and HS-PGA scores among female patients with hidradenitis suppurativa, suggesting its potential as an effective treatment option, even at lower doses, despite no change in Hurley stage or fistula count.
September 2018 in “Cumhuriyet medical journal” This study found that women with severe hirsutism have thicker subcutaneous abdominal fatty tissue and are more likely to develop metabolic syndrome compared to those with moderate hirsutism.
9 citations
,
January 1997 in “Gynecological Endocrinology” This review discusses the regulation of hair growth, causes of excessive androgen secretion, and current safe solutions for hyperandrogenism manifestations in women but reports no new clinical results.
March 1997 in “The Lancet” Hirsutism is abnormal male-pattern hair growth in females due to excess androgens.
January 2016 in “Springer eBooks” This article reviews causes and treatments of hyperandrogenism, including hirsutism and acne, but presents no new clinical findings.