An Endocrinopathy Characterized by Dysfunction of the Pituitary-Adrenal Axis and Alopecia Universalis: Supporting the Entity of a Triple H Syndrome

    September 2002 in “ European Journal of Endocrinology ”
    Kenji Ichiki, Tomoatsu Nakamura, Naruhiro Fujita, K. Honda, Toru Hiraga, Shun Ishibashi, San‐e Ishikawa
    TLDR Triple H syndrome exists and can vary in symptoms.
    The document described a case of a 25-year-old man with triple H syndrome, characterized by ACTH deficiency, alopecia universalis, and anterograde amnesia. The patient experienced systematic hair loss, significant weight loss, and was admitted to the hospital due to unconsciousness. Laboratory tests revealed low plasma glucose and deficiencies in GH and ACTH, along with hypoadrenocorticism. Despite low normal intelligence and minor hippocampal changes, treatment with hydrocortisone normalized glucose levels, restored body weight, and promoted hair growth over 7 months. This case supported the existence of triple H syndrome and suggested variability in its presentation.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 1000+ results

      community Alopecia Areata Question

      in Treatment  2 upvotes 4 years ago
      A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

      community No hair, don't care! [24/F] :)

       59 upvotes 9 years ago
      A woman with alopecia universalis shares her positive experience of being bald, finding it freeing and less worrisome. She also discusses her skincare routine using Korean products.

      community Olumiant alternative for Alopecia Areata?

      in Treatment  1 upvotes 2 years ago
      A user with alopecia areata is considering treatment options like injections or Olumiant but is concerned about cost and whether delaying treatment will lead to permanent hair loss. They are seeking alternative treatments that are more affordable for a college student.

      community Scalp, eyebrow, eyelash and pubic hair loss.

       7 upvotes 7 years ago
      The user experienced significant hair loss on the scalp, eyebrows, eyelashes, and pubic area, along with itchy, flaky skin and red patches. They have a history of eczema and dermatitis and suspect that stopping shampoo use and taking Ritalin may have contributed to the issue.

      community Why Is No One Talking About Chromosome 20?

      in Chat  32 upvotes 2 months ago
      Some hair loss may be linked to chromosome 20, which isn't affected by DHT blockers like finasteride. Treatments like minoxidil, microneedling, and genetic testing are suggested, but their effectiveness for this type of hair loss is uncertain.

    Related Research

    4 / 4 results