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GlossaryCushing's syndrome (hyperadrenocorticism)

condition caused by excessive cortisol, leading to weight gain and skin changes

Cushing's syndrome, also known as hypercortisolism, is a condition characterized by prolonged exposure to high levels of cortisol, a hormone produced by the adrenal glands. This can result from taking corticosteroid medications or from the body producing too much cortisol due to tumors in the pituitary or adrenal glands. Symptoms include weight gain, particularly around the abdomen and face, thinning skin, easy bruising, and in some cases, hair loss or excessive hair growth.

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Suspected Calcinosis Cutis and Demodicosis Secondary to Exogenous Steroid Administration in a Dog with Hypoadrenocorticism

research Suspected Calcinosis Cutis and Demodicosis Secondary to Exogenous Steroid Administration in a Dog with Hypoadrenocorticism

January 2020 in “Frontiers in Medical Case Reports”

A dog developed skin issues from too many steroids, but reducing steroids and using a specific treatment fixed the problems.

research Growth Hormone Deficiency with Late-Onset Hypothalamic Hypoadrenocorticism Associated with Respiratory and Renal Dysfunction: A Case Report

April 2020 in “BMC endocrine disorders”

A woman with childhood growth hormone deficiency had multiple hormone deficiencies and developed serious lung and kidney problems later in life.

Trilostane Treatment of 78 Dogs With Pituitary-Dependent Hyperadrenocorticism

research Trilostane Treatment of 78 Dogs With Pituitary-Dependent Hyperadrenocorticism

149 citations , June 2002 in “Veterinary record/The veterinary record”

Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.

research Long-Term Effects of Trilostane in Dogs with Cushing's Syndrome

January 2011

Trilostane generally improved symptoms in dogs with Cushing's syndrome, but dosage adjustments were needed over time.

research An Endocrinopathy Characterized by Dysfunction of the Pituitary-Adrenal Axis and Alopecia Universalis: Supporting the Entity of a Triple H Syndrome

1 citations , September 2002 in “European Journal of Endocrinology”

Triple H syndrome exists and can vary in symptoms.

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