January 2002 in “Anais Brasileiros De Dermatologia” This article reviews androgen metabolism-related skin conditions like acne and androgenic alopecia, the evaluation of these conditions, and established dermatological therapies, without providing new clinical results.
January 2024 in “International Journal of Health Science” This literature review of hormonal implants in Brazil highlights their expanding usage beyond contraceptive and hormone replacement purposes, noting aesthetic desires like muscle mass gain. However, significant side effects such as cardiovascular events and psychological complications are frequently reported, potentially outweighing the benefits.
2 citations
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January 2017 Personalized treatment is crucial for women with hyperandrogenism-related acne and hirsutism.
6 citations
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January 2020 in “BMC Neuroscience” In this study, male-derived brain tissue exhibited higher cell death following ischemia compared to female-derived tissue, and certain steroid hormones showed different neuroprotective effects depending on the sex of the tissue.
January 2025 in “JCEM Case Reports” Among postmenopausal women, this case study observed that a rare ovarian tumor called thecoma, found via MRI, was associated with high testosterone levels and symptoms of mild virilization such as hirsutism, indicating surgery as the primary treatment.
January 2004 in “Elsevier eBooks” This article discusses drugs with anti-androgenic effects and their mechanisms but reports no new research findings.
6 citations
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October 2007 in “Medical Hypotheses” This article proposes that androgenic alopecia might be an evolutionary mechanism for reducing prostate cancer risk by enhancing UV absorption, rather than being a risk factor.
January 2003 in “Zhonghua shiyan waike zazhi” This study found that androgen is essential for erectile function in rats, and suggests that its effects may be partly mediated through nitric oxide synthase positive neurons in the medial preoptic area.
August 2009 in “International Journal of Dermatology” This case report describes a postmenopausal woman who experienced facial erythema, acne, and hirsutism due to excess androgen and estrogen levels.
4 citations
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June 2017 in “Endocrine Reviews” Dihydrotestosterone (DHT) mainly affects nearby cells, doesn't significantly change prostate hormonal environment or cancer risk, and doesn't play a main role in causing hair loss or acne. More research is needed on its effects on heart health, sexual function, and bone health.
November 2024 in “Benha Journal of Applied Sciences” In this study, the researchers explored how the loss of structural integrity in hair follicles due to reduced α-SMA expression in the vertex area may contribute to androgenetic alopecia.
May 2025 in “Anatolian journal of obstetrics and gynecology research.” This source highlights the essential role of androgens in women's health, noting their impact on various body systems and the critical need for more research on androgen therapies regarding side effects, patient selection, and laboratory standardization.
January 2001 in “대한피부과학회지” This study confirmed that androgenetic alopecia significantly affects the quality of life in male patients, particularly impacting their social experiences and self-perception.
October 2024 in “Cosmoderma” In this review, the authors highlight the importance of hair care for men, suggesting that proper routines and a nutrient-rich diet can help maintain scalp health, prevent hair loss, and promote a sense of well-being.
38 citations
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January 1991 in “International Journal of Dermatology” In this study, men with androgenic alopecia taking minoxidil gel generally showed no evidence of psychological malfunction, but those over 35 experienced greater psychological improvement when they had cosmetic success with the treatment.
5 citations
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January 1985 in “Archives of Dermatology” This article reviews the complex relationship between androgenic hormones and skin disorders, emphasizing the need for further innovative research to understand varying skin responses, but it reports no new findings.
36 citations
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July 2022 in “Journal of Medicinal Chemistry” This review discusses various compounds targeting the androgen receptor, including recent developments in heterobifunctional degraders for prostate cancer treatment, but reports no new clinical results.
15 citations
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December 2019 in “Aesthetic Surgery Journal” This study found that there is a low prevalence and wide variability in U.S. insurance coverage for ancillary gender surgeries, with specific criteria often required for favorable coverage.
131 citations
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September 2010 in “The Laryngoscope” This study found that forehead feminization significantly contributes to recognizing female gender and reported that feminizing forehead cranioplasty is a safe procedure with a low complication rate.
January 2023 in “Open Journal of Endocrine and Metabolic Diseases” This study in Senegal reported that among women with hyperandrogenism, the primary diagnosis was polycystic ovarian syndrome, with symptoms including hirsutism, menstrual disorders, and acne.
29 citations
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May 1988 in “Clinical Endocrinology” Fibroblasts help understand androgen resistance at the cellular level.
December 2020 in “Current Sexual Health Reports” This review discusses the role of neurosteroids and androgens throughout different life stages, noting the potential disruptions caused by 5α-reductase inhibitors like finasteride, but no new clinical results are reported.
3 citations
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February 2025 in “Endocrine” This study emphasizes the necessity of confirming elevated testosterone levels detected by immunoassay with liquid chromatography-tandem mass spectroscopy before pursuing more complex diagnostic evaluations.
January 2026 in “Journal of Sexual and Mental Health” This study reports that two oral hormonal agents, dimethandrolone undecanoate and 11β-methylnortestosterone dodecylcarbonate, may effectively suppress hormones to contraceptive levels in men with mild side effects, though longer-term trials are required to confirm their safety and efficacy.
218 citations
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December 2011 in “Advances in Urology” This review discusses the biochemical properties and clinical significance of 5 alpha-reductase isozymes and reports no new clinical results.
January 2016 in “The Korean Journal of Internal Medicine” This case report presents the first instance in Korea of unilateral gynecomastia and breast pain associated with doxazosin use.
January 1998 in “Dermatologic Surgery” This study found that 42% of healthy men aged 18-49 in a community setting experienced moderate to extensive male pattern hair loss.
March 2026 in “Seven Editora eBooks” This study systematically reviewed the use of topical testosterone products such as creams, gels, and patches, finding they effectively raise serum testosterone but pose significant systemic risks like acne and gynecomastia, necessitating careful medical oversight.
25 citations
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January 2013 in “International Journal of Trichology” In this study, decreased levels of SHBG and a high free androgen index were observed in men with severe premature baldness compared to controls, but this condition was not equivalent to PCOS or metabolic syndrome in females.