Intricate Diagnosis Due to Falsely Elevated Testosterone Levels by Immunoassay

    February 2025 in “ Endocrine
    Benedetta Gardini, Marta Bondanelli, A Cariani, Maria Chiara Zatelli, Maria Rosaria Ambrosio
    TLDR Confirm testosterone levels with advanced tests to avoid unnecessary procedures.
    The document discusses the issue of falsely elevated testosterone levels detected by immunoassay, which may not align with clinical findings. It emphasizes the importance of confirming these results using liquid chromatography-tandem mass spectroscopy before proceeding with more complex diagnostic investigations and care. This approach helps prevent unnecessary and potentially invasive procedures based on inaccurate initial test results.
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