May 2021 in “Journal of the Endocrine Society” This case report highlights the adverse effects of unmonitored bioidentical hormone replacement therapy, emphasizing the need for patient education about its safety and efficacy compared to FDA-regulated hormones.
7 citations
,
July 1981 in “Clinical and Experimental Dermatology” This study found that the normalized androgen ratio (NAR) could help evaluate androgen activity in women with acne vulgaris, hirsutism, and androgenetic alopecia, showing elevated NAR in some patients.
January 2006 in “프로그램북(구 초록집)”
December 2024 in “Indian Journal of Dermatology Venereology and Leprology” Atypical male hair loss may not respond to usual treatments.
9 citations
,
September 2020 in “Journal of Drugs in Dermatology” This study found that men have higher COVID-19 positivity, hospitalization, and death rates than women, even when accounting for age differences.
3 citations
,
November 2020 in “Journal of The American Academy of Dermatology” This paper discusses the proposal that androgenetic alopecia, as seen in the "Gabrin sign", could indicate higher risk of severe COVID-19 symptoms, but its validity is questioned and further confirmation is needed.
9 citations
,
January 2007 in “Endocrine Practice” This case report describes a 60-year-old postmenopausal woman with virilization and hirsutism caused by hilus-cell hyperplasia, which was confirmed following bilateral salpingo-oophorectomy.
January 2022 in “Springer eBooks” This article outlines a diagnostic and therapeutic strategy for female functional androgenization, detailed by guidelines and lifestyle recommendations, but reports no new clinical results.
57 citations
,
February 1983 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that pubic skin fibroblasts respond to androgens, increasing 5α-reductase activity via an androgen receptor-mediated mechanism, suggesting its potential as a marker of androgen action in vitro.
July 2025 in “International Journal Of Literature And Languages” This article examines how national and cultural factors influence gender representation in advertising for medical products, highlighting the need for gender-sensitive language to combat stereotypes.
December 1976 in “PubMed” This review discusses the histology of pilo-sebaceous follicles, androgen receptors, and various treatments for hirsutism and acne in women, but it reports no new clinical results.
This review discusses the role of norepinephrine release and protein kinase C activation in the development of benign prostatic hypertrophy, suggesting potential targets for new therapies, but it reports no new clinical results.
3 citations
,
September 2021 in “The Medical Journal of Cairo University/The Medical Journal of Cairo University” This study found that postadolescent males with acne vulgaris had a higher prevalence of metabolic syndrome compared to controls, but acne severity was not significantly associated with metabolic syndrome occurrence.
1 citations
,
January 2015 Hyperandrogenism in women often causes acne and excess hair, treatable with lifestyle changes and medications.
1 citations
,
November 1995 in “Postgraduate medical journal” This article presents a case of 5-alpha-reductase deficiency in a Saudi individual, reporting no new research findings.
June 2015 in “Obstetrics, gynaecology and reproductive medicine” This article reviews the causes, physiology, and treatment strategies for hirsutism in women, highlighting that effective management often requires addressing underlying conditions and may involve lifestyle changes and pharmacological interventions.
September 2022 in “Annals of medicine and surgery” This case report discusses the diagnostic challenges and management options for three siblings with 46, XY DSD due to type 2 5-α reductase deficiency, highlighting the genetic basis and impact on their quality of life.
59 citations
,
September 2003 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This study suggests that epitestosterone may play a role in regulating androgen-dependent processes like prostate growth and body hair distribution by counteracting testosterone's actions.
November 2004 in “Medical Journal of Indonesia” This review discusses the impact of hormonal changes on female skin and hair loss and suggests that antiandrogenic treatments may help mitigate these effects, but reports no new clinical results.
August 2025 in “Journal of Affective Disorders” This study found that gender-diverse individuals experienced higher depression and anxiety levels alongside lower cortisol concentrations, resembling profiles typical in trauma and pain-related conditions.
January 2012 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” This article discusses the role of androgens in skin conditions like acne and alopecia, emphasizing combined systemic and topical therapy approaches, but it reports no new clinical outcomes.
66 citations
,
January 2001 in “Vitamins and hormones” This chapter reviews the role of androgen receptors in mediating the actions of androgens in specific tissues and provides no new experimental findings.
46 citations
,
November 2014 in “The Journal of Clinical Endocrinology & Metabolism” This study concluded that steroid deficiencies were significantly more severe in men with panhypopituitarism than in those with isolated gonadotropin deficiency.
5 citations
,
August 2022 in “International Journal of Women s Health” Women with hyperandrogenism, especially those with PCOS, are more likely to have psychiatric disorders.
9 citations
,
January 2018 in “American Journal of Men's Health” This study analyzed self-reports from discussion forums to categorize and understand adverse effects experienced by individuals using finasteride, suggesting a need for further investigation into post-finasteride syndrome.
89 citations
,
August 2013 in “PloS one” This study used the "ARE-Luc" mouse model to visualize androgen receptor activity across various tissues in both male and female mice, highlighting the direct action of androgens outside reproductive organs.
2 citations
,
January 1981 Antiandrogens can treat excess body hair and hair loss by blocking male hormones.
25 citations
,
November 1979 in “International Journal of Dermatology” This article reviews the metabolism and action of androgen in the skin but reports no new experimental results; the author calls for further research.
6 citations
,
January 2003 in “Dermatology” This study reviewed 26 cases of X-linked recessive ichthyosis and observed 11 patients with advanced-stage androgenetic alopecia, suggesting a compensatory role of two steroid biosynthesis pathways.