Metabolism and Action of Androgen in the Skin

    November 1979 in “ International Journal of Dermatology ”
    Susumu Takavasu
    TLDR Androgens affect skin conditions like acne and hair loss through specific biochemical pathways.
    The document discussed the metabolism and action of androgens in the skin, focusing on how these hormones influence various skin functions and conditions. It detailed the biochemical pathways through which androgens are metabolized in the skin and their role in conditions such as acne, seborrhea, and androgenetic alopecia. The study highlighted the importance of enzymes like 5α-reductase in converting testosterone to dihydrotestosterone (DHT), which has a more potent effect on skin and hair follicles. The research provided insights into potential therapeutic targets for treating androgen-related skin disorders.
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