Clinical Characteristics of Hyperandrogenism Include Hirsutism, Polycystic Ovary Syndrome, and Acne: Association with Psychiatric Disease in Women - A Nationwide Population-Based Cohort Study in Taiwan
August 2022
in “
International Journal of Women s Health
”
TLDR Women with hyperandrogenism, especially those with PCOS, are more likely to have psychiatric disorders.
This nationwide population-based cohort study in Taiwan examined the link between hyperandrogenism (characterized by hirsutism, polycystic ovary syndrome (PCOS), and acne) and psychiatric disorders in women, involving 9,954 participants with hyperandrogenism and 39,816 controls. It found that women with hyperandrogenism had a higher incidence of psychiatric disorders (13.25% vs. 9.80%), with an adjusted hazard ratio of 2.004, indicating a significant association. Women aged 20-29 were particularly at risk, and PCOS showed a strong association with psychiatric disorders (adjusted HR: 3.165), while hirsutism and acne did not show statistically significant associations. The study emphasized the importance of considering psychiatric risks in women with hyperandrogenism and called for further research to understand the underlying mechanisms.
