Clinical Characteristics of Hyperandrogenism Include Hirsutism, Polycystic Ovary Syndrome, and Acne: Association with Psychiatric Disease in Women - A Nationwide Population-Based Cohort Study in Taiwan

    August 2022 in “ International Journal of Women s Health ”
    Tsan-Min Wang, Cheng-Hao Chou, Yi‐Liang Lee, Chi‐Hsiang Chung, Yao-Ching Huang, Xiao-Cheng Lai, Chien‐An Sun, Chieh-Yi Kang, Gwo‐Jang Wu, Wu‐Chien Chien
    TLDR Women with hyperandrogenism, especially those with PCOS, are more likely to have psychiatric disorders.
    This nationwide population-based cohort study in Taiwan examined the link between hyperandrogenism (characterized by hirsutism, polycystic ovary syndrome (PCOS), and acne) and psychiatric disorders in women, involving 9,954 participants with hyperandrogenism and 39,816 controls. It found that women with hyperandrogenism had a higher incidence of psychiatric disorders (13.25% vs. 9.80%), with an adjusted hazard ratio of 2.004, indicating a significant association. Women aged 20-29 were particularly at risk, and PCOS showed a strong association with psychiatric disorders (adjusted HR: 3.165), while hirsutism and acne did not show statistically significant associations. The study emphasized the importance of considering psychiatric risks in women with hyperandrogenism and called for further research to understand the underlying mechanisms.
    Discuss this study in the Community →

    Research cited in this study

    10 / 10 results

    Related Community Posts Join

    6 / 8 results

      community Dutasteride is amazing even for women with FAGA!

      in Female  151 upvotes 2 months ago
      Dutasteride significantly improved hair health and reduced shedding for a woman with PCOS and hyperandrogenism, without causing depression or anxiety, unlike finasteride. Dutasteride also helped with PMDD symptoms and had no side effects, though it changed hair texture.

      community DHT levels after 4 weeks of Fina and 8 weeks of Fina + 4 weeks of Duta

      in Update  36 upvotes 6 years ago
      The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.

      community Proposed new pathogenesis model for androgenetic alopecia (AGA)

      in Research/Science  6 upvotes 2 years ago
      The conversation discusses a new model for understanding androgenetic alopecia (AGA), linking it to dietary and lifestyle factors similar to PCOS, and highlighting the role of DHT, vascular damage, and inflammation. Treatments mentioned include Minoxidil, finasteride, and RU58841.

      community Spironolactine Update: 2 months (34, Female)

      in Female  20 upvotes 8 years ago
      A female user's experience using Spironolactone to treat Female Pattern Hair Loss (FPHL) and Androgenic Alopecia, as well as discussing the effectiveness of the drug at different dosages.

    Related Research

    4 / 4 results