March 2026 in “Cancer Diagnosis & Prognosis” In this study, researchers used a patient-reported outcome questionnaire to assess long-term adverse effects in breast cancer patients undergoing chemotherapy, finding persistent symptoms like neuropathy, dysgeusia, insomnia, and nail loss. Peripheral neuropathy was notably prolonged in those receiving anthracycline- and taxane-based regimens compared to docetaxel/cyclophosphamide.
5 citations
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May 2017 in “Journal of the European Academy of Dermatology and Venereology” In this study, plasma levels of MSH and cortisol in patients with alopecia areata did not show significant changes compared to healthy controls.
51 citations
,
May 2004 in “American journal of ophthalmology” This study reports that poliosis can be an adverse effect of topical prostaglandin F2α analog therapy in patients treated for primary open angle glaucoma.
6 citations
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January 2024 in “ACS Medicinal Chemistry Letters” This study found that the alkaloids cepharanthine and berbamine bind to SK2 and SK3 channel subtypes with affinities that match their concentrations active against various diseases, prompting further investigation into SK channels' role in their therapeutic effects.
February 2022 in “Journal of Clinical and Experimental Investigations” This study found that patients with Fibromyalgia Syndrome had more frequent skin symptoms and lower quality of life compared to controls, suggesting the need for a multidisciplinary treatment approach.
September 2014 in “Springer eBooks” This review discusses the evaluation and management of breast pain, or mastalgia, highlighting non-pharmacologic therapies and the limited role of surgical interventions, but reports no new clinical findings.
12 citations
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June 2020 in “Sultan Qaboos University medical journal” This review discusses the role of the TRPV4 channel in skin physiology and pathology, highlighting its potential as a therapeutic target for skin disorders, but reports no new clinical results.
1 citations
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July 2024 in “JAAD Case Reports” This study links scalp pruritus in lichen planopilaris and its variants to the inflammation-induced release of substance P and calcitonin gene-related peptide by sensory nerves around hair follicle inflammation sites.
This study examined the relationship between sympathetic nerve endings and alopecia using direct and indirect immunofluorescence on human tissue samples, reporting no new clinical results.
4 citations
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April 2009 in “Journal of Pain” Finasteride boosts morphine's pain relief and prevents tolerance and withdrawal in rats.
35 citations
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December 1979 in “Naunyn-schmiedebergs Archives of Pharmacology” These drugs raise prostaglandin-like material in dog blood, possibly causing blood vessel widening.
April 2020 in “Journal of The American Academy of Dermatology” This letter highlights concerns about transient lymphadenopathy as a potential adverse effect of platelet-rich plasma combined with microneedling for alopecia, emphasizing the need to understand its underlying cause.
1 citations
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July 2024 in “Journal of Investigative Dermatology” Plaquenil can cause a severe skin reaction called AGEP, requiring prompt diagnosis and treatment.
May 2026 in “Journal of Controlled Release” December 2004 in “Neuropsychopharmacology” This study found that chronic ethanol exposure and withdrawal alter the expression and function of GABA-A receptors in rat hippocampal and cerebellar neurons, suggesting different roles for these receptors in controlling tonic inhibition.
74 citations
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February 2011 in “Headache The Journal of Head and Face Pain” This article reviews acute and prophylactic treatments for cluster headaches, highlighting sumatriptan injections, oxygen therapy, and verapamil as effective options, but reports no new clinical results.
35 citations
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January 2005 in “Brain Research” This study indicates that progesterone’s anesthetic activity in PR knockout mice is not due to progesterone receptors but is partially mediated by the neurosteroid allopregnanolone through GABAA receptor potentiation.
15 citations
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March 2007 in “Hormones and Behavior” Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.
46 citations
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April 2021 in “International Journal of Molecular Sciences” This review discusses the potential of curcumin and its formulations to mitigate neuropathic and postoperative pain, highlighting positive outcomes in preclinical and clinical studies but noting the need for further clinical research.
135 citations
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October 1999 in “Journal of Cell Science” This study found that overexpression of PKCα in mouse epidermis increases expression of specific proinflammatory mediators and induces inflammation but does not significantly affect epidermal differentiation, proliferation, or tumor promotion with TPA.
May 2026 in “Iranian journal of pharmaceutical research” This study found that HAMA hydrogels promote faster healing of skin wounds in mice by enhancing the accumulation of anti-inflammatory macrophages and increasing type III collagen in the local wound environment.
12 citations
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March 2016 in “BBA clinical” This study found that intracellular Toll-like receptors were significantly up-regulated in peripheral blood mononuclear cells of alopecia areata patients, suggesting a potential role in inflammatory signaling and pathogenesis.
9 citations
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August 2019 in “Lupus” This study found that body image-related quality of life significantly mediates the relationship between pain and depressive symptoms in patients with systemic lupus erythematosus.
3 citations
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October 2024 in “Experimental Dermatology” This study found that patients with alopecia areata exhibited increased CRHR1 expression on circulating monocytes compared to controls, suggesting that stress-related factors like CRH and CRHR1 may contribute to the development and progression of the condition, particularly in chronic cases and those with larger lesions.
January 2026 in “RSC Advances” This study found that the natural polymer-based hydrogel Gel/SA@PL released growth factors in a controlled way, which enhanced tissue regeneration and minimized scarring in the healing of diabetic wounds.
34 citations
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August 2015 in “Frontiers in Behavioral Neuroscience” This study found that augmenting or reducing allopregnanolone activity in the BNST affected contextual fear expression in rats, suggesting sex differences in anxiety may be linked to neuroactive steroid regulation.
August 2021 in “The Journal of Physiology” This study found that GABA can depolarize murine sensory nerve axons via GABAA receptor activation, with the ß3 subunit being crucial to excitability, and that NKCC1 plays a vital role in mediating this effect.
1 citations
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May 2022 in “Голова и шея.” This study concluded that the anesthesia protocol using fentanyl, propofol, cisatracuria besylate, tranexamic acid, atropine, and metoclopramide resulted in the least pain during septoplasty.
April 2026 in “Applied Materials Today” This study introduced a pH-responsive polymeric wound dressing that enhances healing in chronic wounds by changing shape and drug delivery based on wound pH, achieving a 94.88% healing rate in diabetic mice by day 14.
6 citations
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March 2024 in “Saudi Pharmaceutical Journal” This study found that a nano-cubosome formulation co-loaded with capsaicin and thiocolchicoside enhanced bioavailability and showed promising analgesic and anti-inflammatory effects in rats, potentially benefiting gout management through improved transdermal delivery.