Increased CRHR1 Expression on Monocytes from Patients with AA Enables a Pro-Inflammatory Response to Corticotrophin-Releasing Hormone

    October 2024 in “ Experimental Dermatology ”
    Hongwei Guo, H. C. Lai, Bo‐Quan Long … Kevin J. McElwee
    Studysummary This study found that patients with alopecia areata exhibited increased CRHR1 expression on circulating monocytes compared to controls, suggesting that stress-related factors like CRH and CRHR1 may contribute to the development and progression of the condition, particularly in chronic cases and those with larger lesions.
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    Research cited in this study 14

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