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GlossaryCorticotropin-Releasing Hormone

peptide hormone that triggers stress response via ACTH release

Corticotropin-Releasing Hormone (CRH) is a peptide hormone involved in the stress response. It is produced by the hypothalamus and stimulates the pituitary gland to release adrenocorticotropic hormone (ACTH), which in turn prompts the adrenal glands to produce cortisol, a key stress hormone. CRH also plays a role in various bodily functions, including immune response and skin health, and has been linked to conditions like alopecia, where stress can exacerbate hair loss.

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research The Skin POMC System (SPS): Leads and Lessons from the Hair Follicle

66 citations , October 1999 in “Annals of the New York Academy of Sciences”

The Skin POMC System affects hair growth and skin responses to stress.

research Increased CRHR1 Expression on Monocytes from Patients with AA Enables a Pro-Inflammatory Response to Corticotrophin-Releasing Hormone

3 citations , October 2024 in “Experimental Dermatology”

Higher CRHR1 levels in AA patients lead to increased inflammation.

research Does the Corticotropin-Releasing Hormone System Play a Role in the Pathogenesis of Lichen Planus?

January 2017 in “Postepy Dermatologii I Alergologii”

The CRH/CRH-R1 system might be involved in causing lichen planus.

research Sebocytes’ Makeup: Novel Mechanisms and Concepts in the Physiology of the Human Sebaceous Glands

58 citations , March 2011 in “Pflügers Archiv für die gesamte Physiologie des Menschen und der Tiere/Pflügers Archiv”

Hormones and signaling pathways control sebaceous gland function and could help treat acne.

research Corticotropin-Releasing Hormone and the Skin

137 citations , January 2006 in “Frontiers in bioscience”

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

View more "corticotropin-releasing hormone receptor" in research →

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community How does hair loss and recovery work?

in Chat 12 upvotes 1 year ago

Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

community Result of my cortisol, prolactin, testosterone, ACTH blood test,

in Update 4 months ago

OP is using 5% minoxidil and a foligain supplement for hair loss, with blood test results showing high cortisol levels. OP is considering starting finasteride, while another user shares their experience with finasteride and hair loss challenges due to malabsorption issues.