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GlossaryCorticotropin-Releasing Hormone

peptide hormone that triggers stress response via ACTH release

Corticotropin-Releasing Hormone (CRH) is a peptide hormone involved in the stress response. It is produced by the hypothalamus and stimulates the pituitary gland to release adrenocorticotropic hormone (ACTH), which in turn prompts the adrenal glands to produce cortisol, a key stress hormone. CRH also plays a role in various bodily functions, including immune response and skin health, and has been linked to conditions like alopecia, where stress can exacerbate hair loss.

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research Does the Corticotropin-Releasing Hormone System Play a Role in the Pathogenesis of Lichen Planus?

January 2017 in “Postepy Dermatologii I Alergologii”

The CRH/CRH-R1 system might be involved in causing lichen planus.

research Corticotropin-Releasing Hormone and the Skin

137 citations , January 2006 in “Frontiers in bioscience”

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

research Corticotropin-Releasing Hormone: An Autocrine Hormone That Promotes Lipogenesis in Human Sebocytes

284 citations , May 2002 in “Proceedings of the National Academy of Sciences”

CRH promotes fat production in skin cells, affecting conditions like acne.

New Effects of Caffeine on Corticotropin-Releasing Hormone (CRH)-Induced Stress Along the Intrafollicular Classical Hypothalamic-Pituitary-Adrenal (HPA) Axis (CRH-R1/2, IP3-R, ACTH, MC-R2) and the Neurogenic Non-HPA Axis (Substance P, p75NTR and TrkA) in Ex Vivo Human Male Androgenetic Scalp Hair Follicles

research New Effects of Caffeine on Corticotropin-Releasing Hormone (CRH)-Induced Stress Along the Intrafollicular Classical Hypothalamic-Pituitary-Adrenal (HPA) Axis (CRH-R1/2, IP3-R, ACTH, MC-R2) and the Neurogenic Non-HPA Axis (Substance P, p75NTR and TrkA) in Ex Vivo Human Male Androgenetic Scalp Hair Follicles

12 citations , April 2020 in “British Journal of Dermatology”

Caffeine may help reduce stress-induced hair loss.

research An Implication for Post-Transcriptional Control: Reciprocal Changes of Melanocortin Receptor Type 2 mRNA and Protein Expression in Alopecia Areata

7 citations , October 2010 in “Medical Hypotheses”

Alopecia areata may involve stress-related changes affecting hormone receptors, leading to reduced cortisol production.

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community How does hair loss and recovery work?

in Chat 12 upvotes 1 year ago

Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

community Result of my cortisol, prolactin, testosterone, ACTH blood test,

in Update 1 month ago

OP is using 5% minoxidil and a foligain supplement for hair loss, with blood test results showing high cortisol levels. OP is considering starting finasteride, while another user shares their experience with finasteride and hair loss challenges due to malabsorption issues.