research The Biological Actions of Dehydroepiandrosterone Involve Multiple Receptors
DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
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570-600 / 846 resultsresearch Sex Hormones and Acne: The Role of the Skin as an Endocrine Organ
Sex hormones, especially androgens, play a key role in causing acne.
research 5α-Reductases in Human Physiology: An Unfolding Story
We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.
research Current Understanding of Androgenetic Alopecia: Part I - Etiopathogenesis
research Mechanism of Action of Androgen in Hair Follicles
Testosterone affects hair follicles differently across body sites, with beard hair follicles showing more activity of a specific enzyme and presence of androgen receptors compared to scalp hair.
research Molecular Basis of Androgenetic Alopecia
research Mineralocorticoid Receptor Antagonists: A New Sprinkle of Salt and Youth
MR antagonists may improve skin health and wound healing, especially in aging.
research Androgenetic Alopecia
Minoxidil was promising for treating male and female pattern baldness in 1994, but more research on genetics and other treatments was needed.
research Challenges in Treatment of Patients With Non-Classic Congenital Adrenal Hyperplasia
Treating non-classic congenital adrenal hyperplasia is complex because the benefits of hormone treatment must be weighed against potential health risks.
research Androgens and Androgen Receptor in the Management of Skin Diseases
Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.
research Nucleus-Specific Modulation of Phasic and Tonic Inhibition by Endogenous Neurosteroidogenesis in the Murine Thalamus
Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.
research 5α-Reductases in Human Physiology: An Unfolding Story
Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.
research Monitoring of Cortisone and Cortisol Levels in Hair During Pregnancy
Cortisone and cortisol levels in pregnant women’s hair increase as labor approaches, indicating higher stress.
research New Developments in Our Understanding of Acne Pathogenesis and Treatment
We now understand more about what causes acne and this could lead to better, more personalized treatments.
research Androgen Biosynthetic Pathways in the Human Prostate
DHT in the human prostate is produced through multiple pathways, not just from testosterone.
research Intracrine Androgen Biosynthesis, Metabolism, and Action Revisited
The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
research Current Concepts of Polycystic Ovary Syndrome
PCOS is often caused by hormonal imbalances that can lead to various health issues and may indicate a risk for future metabolic and cardiovascular problems.
research Clinical Biochemistry of Dihydrotestosterone
Understanding how DHT works is important for diagnosing and treating hormone-related disorders.
research Essential Fatty Acid Deficiency and Its Effects Upon Reproductive Organs of Male Rabbits
Lack of essential fatty acids in diet causes reproductive issues and poor health in male rabbits.
research A Randomized Placebo-Controlled Study on the Effects of Pioglitazone on Cortisol Metabolism in Polycystic Ovary Syndrome
Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.
research May Patients Receiving 5-Alpha-Reductase Inhibitors Be at Higher Risk of COVID-19 Complications?
Men on 5-alpha-reductase inhibitors might have worse COVID-19 outcomes.
research Ovine Placental Steroid Synthesis and Metabolism in Late Gestation
Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.
research Allopregnanolone Alters the Gene Expression Profile of Human Glioblastoma Cells
Allopregnanolone changes gene expression in glioblastoma cells.
research New Insights Into Testosterone Biosynthesis: Novel Observations From HSD17B3 Deficient Mice
Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.
research Simultaneous LC-MS/MS Quantification of Glucocorticoids, Melatonin, and Its Metabolites in Hair
The new method can measure sleep-related hormones in hair effectively and could help track long-term sleep patterns.
research Ashwagandha Root in the Treatment of Non-Classical Adrenal Hyperplasia
Ashwagandha may improve hormone levels and reduce hair loss in non-classical adrenal hyperplasia.
research Minoxidil Acts as an Antiandrogen: A Study of 5α-Reductase Type 2 Gene Expression in a Human Keratinocyte Cell Line
Minoxidil may help treat hair loss by reducing the activity of a specific enzyme linked to baldness.
research Glucocorticoids and Mineralocorticoids in Hair: Facilitating Accurate Diagnosis of Adrenal-Related Endocrine Disorders
Hair analysis can help diagnose adrenal disorders non-invasively.
research Ectoin Attenuates Cortisone-Induced Skin Issues by Suppression of GR Signaling and the UVB-Induced Overexpression of 11β-HSD1
Ectoin helps prevent cortisone-induced skin problems and supports skin health.
research Sex Chromosome Related Dimorphism in Steroidogenic Enzymes and Androgen Receptor in Response to Testosterone Treatment: An In Vitro Study on Human Primary Skeletal Muscle Cells
Chromosomal differences affect how muscle cells respond to testosterone.