Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, oral dienogest combined with ethinylestradiol provided effective contraception with a Pearl Index of approximately 0.2 and improved androgenic symptoms without significant metabolic effects.

This article provides guidelines for molecular genetic testing of congenital adrenal hyperplasia due to 21-hydroxylase deficiency, focusing on quality requirements, methodologies, and variant classification; it reports no new clinical results.

In this study, researchers developed a method to control the valence states of Mo in nanozymes, optimizing their activity for ROS-related therapies, particularly acute kidney injury treatment, and enabling real-time monitoring with photoacoustic imaging.

N,N-Dimethylglycine sodium salt may improve skin health and treat hair loss.

This study found that SHJH hr mice, with a Hairless gene mutation, exhibit accelerated skin aging potentially due to poor antioxidative protection, highlighting the Hr gene's role in skin aging.

This study reported that a composite hydrogel made with Chlorella-derived extracellular polysaccharide–selenium nanoparticles showed strong antibacterial and anti-inflammatory effects in vitro and significantly accelerated wound healing in vivo, offering potential for managing infected wounds and monitoring healing progression.

This study investigated the electron transfer processes in an iron-mediated DAMO–anammox system, finding that Fe3+ accelerated c-type cytochrome-mediated electron transfer and suggested that riboflavin acts as an electron shuttle and DIET may occur among these microorganisms.

This case report describes acute liver injury in a 5-year-old Caucasian girl after ingesting the Chinese herbal product Shou-Wu-Pian, suggesting a potential link between this unregulated herbal remedy and hepatotoxicity.

This study identified key natural compounds such as polyphenols and flavonoids in tongue fern and established optimal extraction conditions using methanol.

Oral minoxidil 7.5 mg for hair loss increases heart rate but not blood pressure.

This study reported that peginterferon alpha-2a showed high early and sustained virologic response rates in Albanian hemodialyzed patients with hepatitis C, despite causing several adverse effects.

In this study, methanolic extracts of Hibiscus rosa-sinensis showed higher phenolic and flavonoid content, as well as greater concentrations of gallic acid and quercetin, than aqueous extracts, despite the latter yielding more extract, highlighting the effectiveness of methanol for extracting bioactive phytochemicals.

This study describes a method to estimate endogenous hormone production by neutralizing an endogenous hormone with an oppositely acting hormone.

This study suggests that topical application of a hydrogel containing magnetized saline water may promote wound healing in stage 2-3 pressure ulcers in elderly patients by stimulating autophagy, based on observed clinical improvements in a case series.

In this study, oral administration of blue honeysuckle fruit extract was found to promote hair growth in mice by enhancing dermal papilla cell proliferation and activating β-catenin signaling, suggesting its potential use as a food or cosmetic product for hair regeneration.

In this study, low-dose oral minoxidil was found to have a favorable safety profile for treating alopecia, with mostly mild side effects, in both general and hypertensive populations.

In this study, a novel compound named AH-001 demonstrated effective androgen receptor protein degradation, reducing hair loss progression in a mouse model of androgenetic alopecia, with minimal systemic exposure and side effects, suggesting potential for safer treatment.

This study suggests that hesperidin may regulate pathways in hair follicle cells to help mitigate hair loss, revealing molecular mechanisms of nitric oxide donor-mediated hair follicle protection.

This study reported that an injectable hydrogel microparticle vaccine platform enhanced antibody responses and protection against influenza in mice, outperforming the traditional adjuvant aluminum hydroxide.

This study identified that Mangkokan leaf extracts contain active compounds such as alkaloids, flavonoids, steroids, tannins, phenols, and saponins, using different solvents and FTIR analysis.

In this study, researchers found that 4-Octyl itaconate (4-OI) inhibited cisplatin-induced ferroptosis and protected auditory cells by activating the NRF2/HO-1 signaling pathway, suggesting a potential therapeutic approach for reducing hearing loss associated with cisplatin treatment.

This study found that HET extract increased dorsal hair density and VEGF protein expression in a hair growth animal model suggesting its potential efficacy for alopecia treatment.

In this study, hibiscus leaf extract hair tonic at 10% concentration showed better hair growth promotion activity compared to minoxidil 2% in a rabbit model, although it caused eye irritation.

This study found that high doses of cloforex and chlorphentermine caused pulmonary lipid histiocytosis and toxic effects in rats, but did not induce pulmonary hypertension.

This study highlights the approval of orforglipron under the FDA's National Priority Voucher program, emphasizing its significance as a convenient oral treatment option with beneficial effects on glycemic and lipid profiles for diabetes and obesity management.

This study reported that a newly developed hydrogel patch, designed to recruit regulatory T cells through ROS-triggered release of CCL22, improved wound healing and hair follicle regeneration in a diabetic mouse model by scavenging ROS, thereby protecting Tregs and suppressing Th17 cells.

In this study, bovine testes hyaluronidase accelerated wound healing in vitro and in vivo by enhancing cellular proliferation, reepithelialization, and modulating inflammation in rat models.

In this study, women experiencing hair thinning who consumed tailored botanical-based nutraceuticals saw significant increases in linear hair growth rate and other hair health parameters over 90 and 180 days, supporting their effectiveness across different life stages.

A woman with a specific mutation causing adrenal gland issues faced fertility problems, but careful hormone therapy helped her manage it successfully.

This study reported a case of hereditary vitamin D–resistant rickets caused by a single heterozygous missense mutation in the VDR gene, showing dominant-negative effects and reduced response to 1,25-dihydroxyvitamin D3.