9 citations,
May 2010 in “Journal of Investigative Dermatology” Human sebaceous glands can grow back in skin grafts on mice and work like normal human glands.
3 citations,
May 2017 in “British journal of dermatology/British journal of dermatology, Supplement” Certain cells around hair follicles help improve skin regeneration for potential use in skin grafts.
131 citations,
November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.
September 2024 in “Journal of the American Academy of Dermatology” Minoxidil helps hair regrowth and has anti-aging effects on hair follicles.
2 citations,
August 2011 in “InTech eBooks” New methods for growing skin cells can improve skin grafts by building blood vessels within them.
27 citations,
July 1997 in “PubMed” The harlequin ichthyosis mouse mutation causes thick skin and early death, resembling a human skin disorder.
184 citations,
December 2018 in “Nature Communications” Researchers created human hair follicles using a new method that could help treat hair loss.
15 citations,
September 2007 in “Cell & tissue research/Cell and tissue research” Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.
44 citations,
January 2013 in “BMC Dermatology” TGFβ signaling prevents sebaceous gland cells from producing fats.
75 citations,
October 2012 in “Journal of Investigative Dermatology” Alopecia areata can be triggered by specific immune cells without genetic or environmental factors.
41 citations,
June 2013 in “PLOS ONE” Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
27 citations,
October 1999 in “Experimental and Molecular Pathology” Stump-tailed macaque best for researching hair loss causes and treatments.
120 citations,
August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.
43 citations,
July 2019 in “Stem Cells International” Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
69 citations,
June 2017 in “Experimental Biology and Medicine” Advanced human skin models improve drug development and could replace animal testing.
29 citations,
April 2020 in “Journal of Tissue Engineering and Regenerative Medicine” The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
27 citations,
August 2006 in “Laboratory Investigation” SCF and ET-1 together significantly increase skin pigmentation and melanin production.
April 2018 in “Deleted Journal” Skin grafts are a common, minimally invasive way to close wounds in dogs, but better methods are still being sought.
47 citations,
March 2017 in “Materials Science and Engineering: C” Human amniotic membrane helps heal skin wounds faster and with less scarring.
39 citations,
September 2011 in “Tissue Engineering Part B-reviews” Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.
31 citations,
January 2021 in “Experimental Dermatology” Skin organoids are a promising new model for studying human skin development and testing treatments.
1 citations,
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Printing human stem cells and a special matrix during surgery can help grow new skin and hair-like structures in rats.
36 citations,
May 2016 in “Biomaterials” Endo-HSE helps grow hair-like structures from human skin cells in the lab.
3 citations,
May 2021 in “Archiv der Pharmazie” SUN11602 and ONO-1301 could help in skin healing and creating artificial skin.
133 citations,
July 2020 in “Cells” Creating fully functional artificial skin for chronic wounds is still very challenging.
10 citations,
June 2019 in “Journal of Tissue Engineering and Regenerative Medicine” Scientists successfully grew new hair follicles in regenerated mouse skin using mouse and human cells.
353 citations,
July 2015 in “Molecular immunology” Porcine skin is very similar to human skin, making it a useful model for research.
256 citations,
October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Growing human skin cells in a 3D environment can stimulate new hair growth.
10 citations,
September 2022 in “Advanced Healthcare Materials” Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
August 2023 in “International Journal of Molecular Sciences” Human skin xenografting could improve our understanding of skin development, renewal, and healing.