June 2026 in “arXiv (Cornell University)” This study proposes a new test for genome-wide association studies that incorporates Hardy-Weinberg equilibrium into SNP analysis, demonstrating improved power and interpretability over traditional methods, as evidenced by simulations and an alopecia study dataset.
26 citations
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August 2009 in “Journal of Pediatric Gastroenterology and Nutrition” This study reports that gastrointestinal problems, such as intractable diarrhea and enterocolitis, can dominate the clinical course of patients with Hoyeraal-Hreidarsson syndrome and may occur before hematological and immunological symptoms.
1 citations
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July 2024 in “Skin Research and Technology” This study found that patients with androgenetic alopecia had thinner scalp and subcutaneous tissues, narrower and shorter hair follicles, a lower hair follicle count, and fewer color flow signals compared to healthy volunteers, as measured by 22 MHz ultrasound.
December 2013 in “Macedonian Journal of Medical Sciences” This case report describes a 69-year-old woman with hirsutism and elevated serum testosterone, where surgery resolved symptoms and serum testosterone, suggesting ovarian steroid cell tumor consideration in similar profiles.
3 citations
,
May 2025 in “Clinical Endocrinology” Evaluate and manage androgen excess in women with a systematic approach, considering both physical and psychological impacts.
June 2026 in “International Journal of Reproduction Contraception Obstetrics and Gynecology” This study found that serum Anti-mullerian hormone (AMH) levels are significantly elevated in women with polycystic ovary syndrome and can serve as a useful biomarker for diagnosis, especially when ultrasonography is unavailable.
9 citations
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May 2010 in “Gynecological Endocrinology” In this study, echocardiographic measures of cardiac function in women with polycystic ovary syndrome were found to be similar to those of healthy women.
20 citations
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June 2007 in “Recent Patents on Endocrine, Metabolic & Immune Drug Discovery” This review summarizes recent research and patents on 17β-HSD3, 17β-HSD5, and 3α-HSD3 inhibitors, suggesting their potential in treating androgen-dependent diseases, but reports no new clinical results.
1 citations
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May 2018 in “Clinical chemistry” This case report described a 9-year-old girl initially suspected to have complete androgen insensitivity syndrome, whose laboratory tests later suggested an alternative diagnosis involving atypical steroid metabolism patterns and hormonal responses.
13 citations
,
September 2008 in “Experimental and Clinical Endocrinology & Diabetes” This study compared the echocardiographic profiles of patients with polycystic ovary syndrome to those of healthy subjects using conventional methods and tissue Doppler imaging, but it reports no specific findings here.
15 citations
,
October 2018 in “Reproductive Biomedicine Online” This study suggests that the anogenital distance measure AGDAC may moderately discriminate the presence of polycystic ovarian syndrome and could be a useful clinical tool.
32 citations
,
August 2020 in “American Journal Of Pathology” This study reports that in ovarian high-grade serous carcinoma, overexpressed S100A4 likely promotes epithelial-mesenchymal transition and cancer stem cell properties, affecting tumor behavior through its interaction with NMIIA and mutant p53.
1 citations
,
January 2024 in “Archives of Endocrinology and Metabolism” This study found that self-assessed mFG and Hirsuta scores have low specificity for diagnosing hirsutism in clinical settings, though they may still be useful for screening in epidemiological studies.
October 2024 in “Journal of the Endocrine Society” In this case report, a 62-year-old woman with hyperandrogenism and polycythemia was diagnosed with a rare ovarian steroid cell tumor, highlighting the importance of considering such tumors in similar presentations; surgical removal led to symptom and lab normalization.
June 2023 in “Journal of Liaquat University of Medical & Health Sciences” This study observed that women with PCOS from Khyber Pakhtunkhwa had significantly higher serum PSA levels, which positively correlated with hirsutism, testosterone, and DHEAS levels compared to healthy controls.
39 citations
,
January 2009 in “Journal of Ovarian Research” This study found moderate to poor agreement among observers assessing ultrasonographic features of polycystic ovaries, suggesting the need for standardized training modules to improve consistency.
4 citations
,
June 2021 in “Dermatology” This study validated the HS 3D-SeboSkin model as a reliable tool for preclinical research, effectively preserving the structure and biomarker expression of lesional and perilesional HS skin ex vivo.
5 citations
,
January 2023 in “Fertility and sterility” This review discusses the emerging considerations and challenges of uterus transplantation for transgender women but presents no new clinical results.
5 citations
,
February 2022 in “Supportive Care in Cancer” This study found that age is the most significant risk factor for hemorrhagic cystitis after hematopoietic stem-cell transplantation, with additional risk factors including cyclophosphamide-based prophylaxis and, among male recipients, prostatic hyperplasia.
September 2024 in “Brazilian Journal of Case Reports” In this case study, a 62-year-old woman with severe hyperandrogenism underwent a clomiphene test, which suggested an ovarian origin for her condition, leading to the discovery of a Leydig cell tumor after a bilateral oophorectomy.
Hyperandrogenism is diagnosed using clinical signs, lab tests, and imaging.
October 2025 in “Journal of the Endocrine Society” In this case study, a 68-year-old woman with hyperandrogenism and presumed ovarian origin responded well to GnRH agonist therapy, normalizing testosterone levels and stabilizing blood pressure, suggesting its effectiveness as a non-surgical treatment option.
December 1997 in “Journal of The European Academy of Dermatology and Venereology” In this study, hormonal abnormalities were detected in all investigated hirsute Saudi women, with elevated major androgens in 85.9% and polycystic ovaries in 59% of cases.
This review summarizes recent genetic research on hidradenitis suppurativa, highlighting potential therapeutic targets and genetic mutations, but reports no new clinical findings.
4 citations
,
March 2012 in “Our Dermatology Online” This study conducted physical examinations on fifty women with hirsutism, focusing on virilization signs, but reports no new clinical findings.
October 2023 in “Journal of the Endocrine Society” This case report describes a rare instance of hyperandrogenism and increased hirsutism associated with endometrial cancer in a postmenopausal woman, with symptoms resolving and androgen levels normalizing after a total laparoscopic abdominal hysterectomy and bilateral oophorectomy.
October 2023 in “IJEM case reports” This case report describes the diagnosis and management of a 15-year-old girl with complete androgen insensitivity syndrome, highlighting the importance of thorough physical exams for early detection and treatment planning.
56 citations
,
September 2013 in “Experimental Dermatology” This guide reviews the biology of sebaceous glands and their evaluation methods, emphasizing their roles beyond lipid production in skin health and disease, and reports no new research results.
May 2021 in “Journal of the Endocrine Society” This report presents a rare case of suspected 3β HSD deficiency in an adult female with symptoms like male pattern hair loss and low testosterone, suggesting a non-classical presentation.
4 citations
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April 2019 in “Gynecological Endocrinology” This study found that the rs 1570360 polymorphism and the T-G-C haplotype of the VEGF gene may be associated with a protective factor against polycystic ovary syndrome in a Brazilian population.