TLDR Older age is the main risk factor for hemorrhagic cystitis after stem cell transplants.
The study analyzed 237 patients undergoing allogeneic hematopoietic stem-cell transplantation to identify risk factors for hemorrhagic cystitis (HC). HC occurred in 17% of patients, with a higher incidence in males (21% vs 11%). Key risk factors included age over 55, male gender, HLA mismatch, reduced intensity conditioning, and cyclophosphamide-based GVHD prophylaxis. In males, prostatic hyperplasia was an independent risk factor, with 32% of those affected developing HC. HC was associated with longer hospital stays and increased non-relapse mortality. The study concluded that age was the most significant risk factor, suggesting the need for more intensive prophylactic strategies in high-risk patients.
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October 2021 in “Research Square (Research Square)” Older age and prostatic hyperplasia in males increase the risk of hemorrhagic cystitis after stem cell transplantation.
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January 2016 in “International Journal of Trichology” The conclusion is that more hair loss (androgenetic alopecia) is linked to larger prostate size, suggesting hair loss could be an early sign of benign prostatic hyperplasia.
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