Relationship of Serum Prostate-Specific Antigen with Hirsutism in Women with Polycystic Ovary Syndrome in Khyber Pakhtunkhwa, Pakistan

June 2023 in “ Journal of Liaquat University of Medical & Health Sciences ”

Naheed Khattak, Sadaf Durrani, Sobia Ali, Kalsoom Tariq, Ubaid ur Rahman, Ahmed Khan

prostate-specific antigen hirsutism polycystic ovary syndrome testosterone DHEAS PSA PCOS dehydroepiandrosterone sulfate

TLDR Higher PSA levels are linked to more hirsutism in women with PCOS.

The study investigated the relationship between serum prostate-specific antigen (PSA) and hirsutism in women with polycystic ovary syndrome (PCOS) in Khyber Pakhtunkhwa, Pakistan. Conducted from June to December 2021, it involved 172 participants, with 86 newly diagnosed PCOS cases and 86 healthy controls. Results showed significantly higher serum PSA levels in PCOS females (0.325±0.243 vs. 0.119±0.209, P <0.0001), along with increased testosterone and DHEAS levels. A strong positive correlation was found between PSA and hirsutism, as well as with testosterone and DHEAS levels. The study concluded that elevated PSA is significantly associated with hirsutism in PCOS women.

View this study on doi.org →

Discuss this study in the Community →

Research cited in this study

12 / 12 results

research Hirsutism, Normal Androgens, and Diagnosis of PCOS

63 citations , August 2022 in “Diagnostics”

Hirsutism can occur in women with PCOS even if their androgen levels are normal, making diagnosis challenging.

research Serum Prostate Specific Antigen Levels in Women with Androgenetic Alopecia

April 2019 in “Turkderm”

Women with androgenetic alopecia (hair loss) have normal prostate specific antigen levels but higher testosterone levels.

research The Modified Ferriman-Gallwey Score and Hirsutism Among Filipino Women

22 citations , January 2019 in “Endocrinology and metabolism”

An mFG score of 7 or higher indicates hirsutism in Filipino women, often linked to higher free testosterone levels.

research Comprehensive Overview of Polycystic Ovary Syndrome

883 citations , August 2016 in “Nature Reviews Disease Primers”

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

research Hirsutism in Polycystic Ovary Syndrome: Pathophysiology and Management

47 citations , July 2016 in “Current pharmaceutical design”

The document concludes that managing hirsutism in PCOS involves long-term treatment guided by severity, using oral contraceptives and possibly antiandrogens, with attention to individual patient needs.

research Prostate Specific Antigen in Diagnosis of Polycystic Ovarian Syndrome: A New Insight

6 citations , July 2016 in “Gynecological Endocrinology”

PSA levels are higher in women with PCOS, but FAI is a more accurate marker for diagnosis.

research Serum Prostate Specific Antigen Level in Women with Polycystic Ovary Syndrome

1 citations , July 2016 in “Mağallaẗ Kulliyyaẗ al-ṭibb Baġdād”

Women with PCOS have higher PSA levels, which are linked to increased male hormone levels and hirsutism.

research Prostate-Specific Antigen as a Marker of Hyperandrogenism in Women and Its Implications for Antidoping

8 citations , June 2016 in “Clinical Chemistry”

PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.

research Polycystic Ovary Syndrome: Etiology, Pathogenesis, and Diagnosis

991 citations , January 2011 in “Nature Reviews Endocrinology”

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

research Visually Scoring Hirsutism

288 citations , June 2009 in “Human reproduction update”

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

research Androgens and Hair Growth

209 citations , September 2008 in “Dermatologic Therapy”

Androgens can both increase and decrease hair growth in different parts of the body.

research Is Prostate-Specific Antigen a Potential New Marker of Androgen Excess in Polycystic Ovary Syndrome?

16 citations , April 2007 in “Journal of Obstetrics and Gynaecology Research”

Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.

Related Community Posts Join

6 / 835 results

community Dermatologist told me to quit fin after turning 40

in Finasteride/Dutasteride 194 upvotes 2 years ago

A dermatologist advised a patient to stop taking finasteride (fin) after turning 40 due to potential risk of aggressive prostate cancer. The patient and others in the conversation debated this advice, discussing the relationship between finasteride, prostate cancer, and hair loss, and considering alternatives like topical finasteride.

community 4 months progress / dut 0.5mg + topical min

in Progress Pictures 108 upvotes 1 year ago

The conversation is about someone's 4-month hair regrowth progress using 0.5mg dutasteride and topical minoxidil. Another person is inspired and is using 5mg finasteride and 5% minoxidil topically twice daily, hoping for similar results.

community 28M Starting Finasteride for Accelerating Hair Loss – Seeking Monitoring Advice

in General 180 upvotes 1 month ago

The user plans to start a 12-month finasteride treatment to combat aggressive hair loss, with regular monitoring of thyroid levels, testosterone, DHT, liver enzymes, PSA, and iron levels. They seek advice on additional monitoring and aim to balance results with minimal side effects.

community Interpreting pre-finisteride blood panels

in Chat 2 upvotes 6 months ago

The conversation is about someone planning to start finasteride for hair loss and wanting to interpret pre-treatment blood panels to assess the risk of side effects like gynecomastia. They list various tests to measure hormone levels and other health indicators.

community Pre-Finisteride DHT & Hormone Blood Panel

in Finasteride/Dutasteride 3 upvotes 7 months ago

The conversation discusses the cost and insurance coverage of a comprehensive hormone and DHT blood panel for hair loss, with a focus on finasteride treatment. The user seeks a cheaper alternative to a $700 panel recommended in a video.

community 42yo male. This stuff works for older dudes too

in Progress Pictures 817 upvotes 11 months ago

A 42-year-old male shared his hair regrowth progress using a regimen of oral dutasteride, topical minoxidil, and finasteride, along with testosterone injections. He experienced noticeable improvement in hair growth and expressed gratitude for the support and information from the community.

Related Research

1 / 1 results

research Relationship of Serum Prostate-Specific Antigen with Hirsutism in Women with Polycystic Ovary Syndrome in Khyber Pakhtunkhwa, Pakistan

June 2023 in “Journal of Liaquat University of Medical & Health Sciences”

Higher PSA levels are linked to more hirsutism in women with PCOS.