September 2023 in “Acta dermato-venereologica” This study found that pilonidal sinus disease is a common comorbidity with hidradenitis suppurativa and is linked with increased disease severity, suggesting it may serve as a sentinel event for identifying high-risk patients.
11 citations
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February 2008 in “British journal of nursing” This article reviews idiopathic hirsutism, focusing on its definition, diagnosis, causes, and treatment options, without presenting new clinical findings.
November 2021 in “SPAST Abstracts” In this study, EFH-SLM cream demonstrated greater efficiency in reducing hair density compared to plain EFH cream in Swiss albino female mice, with significantly less skin irritation and inflammation observed, suggesting improved permeability and effectiveness of EFH when using the new cream formulation.
23 citations
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June 1945 in “Annals of Internal Medicine” This clinical study explores the causes, progression, and treatment of hirsutism in females, noting its association with tumors in endocrine glands, but does not report new clinical results.
August 2022 in “JAAD case reports” This case report describes a 36-year-old woman with hidradenitis suppurativa whose condition progressed to rapidly fatal squamous cell carcinoma, highlighting the potential for aggressive tumor development linked to specific protein markers.
48 citations
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July 2018 in “Journal of The American Academy of Dermatology” This study observed that treatment with spironolactone significantly improved pain, inflammatory lesion count, and HS-PGA scores among female patients with hidradenitis suppurativa, suggesting its potential as an effective treatment option, even at lower doses, despite no change in Hurley stage or fistula count.
127 citations
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June 2008 in “British Journal of Clinical Pharmacology” This study supports the conclusion that the hormetic dose-response model is the most prevalent and fundamental model in biological and biomedical sciences, applicable to a wide range of clinical conditions.
November 2025 in “Journal of the European Academy of Dermatology and Venereology” In this study, single-cell RNA sequencing of hair follicle populations from hidradenitis suppurativa patients identified three endotypes, suggesting distinct epithelial-immune interactions that may guide stratified therapeutic approaches.
May 2021 in “Journal of the Endocrine Society” This report presents a rare case of suspected 3β HSD deficiency in an adult female with symptoms like male pattern hair loss and low testosterone, suggesting a non-classical presentation.
51 citations
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October 2002 in “European journal of endocrinology” This study found that both high-dose and low-dose finasteride significantly reduced hirsutism scores in women after 12 months, with the lower dose being safe and cost-effective.
December 2005 in “The Sri Lanka Journal of Dermatology” Many young Sri Lankan women entering university have excessive hair growth.
January 2024 in “Advances in Dermatology and Allergology” This review explores the inflammatory pathogenesis and clinical presentation of hidradenitis suppurativa, highlighting the complexity of treatment and the impact on patients' quality of life, while also examining emerging therapeutic options.
12 citations
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January 2012 in “Dermatology” Finasteride helped treat a 28-year-old's facial skin condition.
1 citations
,
August 2024 in “SAR Journal of Pathology and Microbiology” This study observed that among Iraqi women with hirsutism, most had hypothyroidism and elevated hormone levels, particularly DHEAS and testosterone, with acne being the most common associated clinical feature.
4 citations
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August 2019 in “Actas Dermo-Sifiliográficas” This study evaluated the Spanish version of the Hair Specific Skindex-29 questionnaire and found it sensitive to changes in health-related quality of life among women with female-pattern hair loss.
January 2020 in “Przegla̧d dermatologiczny” This article presents a clinical approach to diagnosing and managing hirsutism from a dermatological perspective, but it reports no new clinical findings.
4 citations
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November 2022 in “Acta dermato-venereologica” This study found that patients with hidradenitis suppurativa had lower trabecular bone score and total hip bone mineral density compared to controls, with a high prevalence of vitamin D deficiency.
9 citations
,
July 2017 in “Case Reports in Dermatology” This case study describes a 19-year-old female with hidradenitis suppurativa whose symptoms and metabolic abnormalities improved significantly over 3 years on a combined regimen, though some skin lesions persisted.
7 citations
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June 2000 in “Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Māzandarān/Journal of Mazandaran University of Medical Sciences” In this study, older age and fewer hepatitis vaccinations were linked to lower HBV antibody responses in nursing staff, with antibody levels declining over five years, suggesting a potential need for booster doses.
December 2023 in “Health economics and management review” In this descriptive research conducted in Tirunelveli City, Tamil Nadu, the study identified common health problems among radiographers, including tiredness, body pain, and emotional disturbances, highlighting the need to address these issues to ensure accurate disease diagnosis and treatment in healthcare settings.
24 citations
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March 1996 in “Postgraduate Medical Journal” In this study, most women with hirsutism and regular menstrual cycles were diagnosed with polycystic ovary syndrome, suggesting limited use of the term 'idiopathic or racial' hirsutism without thorough evaluation.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that skin organoids derived from iPSCs with an HS-associated NCSTN mutation showed defects in hair follicle stem cell differentiation and increased expression of inflammatory proteins related to hidradenitis suppurativa.
10 citations
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May 2024 in “Lasers in Surgery and Medicine” This study found that laser hair removal effectively reduces disease severity in hidradenitis suppurativa with minimal side effects, likely due to the destruction of hair follicle units.
22 citations
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January 2008 in “Physiological Research” This review discusses the role of steroid sulfatase in steroid hormone metabolism and highlights the need for more research on its expression and regulation, especially regarding hormone-dependent tumors.
December 1920 in “The Lancet” The document discusses various public health initiatives and societal issues, emphasizing early intervention and support.
1 citations
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July 2024 in “International Journal of Biological Research” This study found that a high percentage of pediatric sickle cell disease patients have parents from medium-high socioeconomic status, indicating that the educational background of parents did not influence the disease's prevalence.
January 2025 in “Excellence in Pediatrics Abstracts” In this study, 55 pediatric patients with hidradenitis suppurativa were assessed, revealing common comorbidities like obesity and acne, a frequent delay in diagnosis, and that most patients experienced symptom improvement with treatment including antibiotics and hormone therapy.
20 citations
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December 2019 in “International Journal of Molecular Sciences” This study found that preconditioning adipose-derived stem cells with HB-EGF enhanced their ability to promote hair growth in vivo by increasing their motility, paracrine effects, and survival.
October 2025 in “Frontiers in Toxicology” This study found that a human relevant potency threshold for estrogen receptor alpha agonism may serve as a health-protective screening tool, and highlights inference performance as essential for scientific confidence frameworks.
46 citations
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July 1974 in “The Journal of Clinical Endocrinology & Metabolism” In this study, women with hirsutism and amenorrhea showed lower serum estradiol and sex hormone binding globulin concentrations but higher levels of unbound testosterone compared to normal individuals.