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In this study, women with hirsutism and amenorrhea showed lower serum estradiol and sex hormone binding globulin concentrations but higher levels of unbound testosterone compared to normal individuals.

This study found that the ethyl acetate fraction of Hibiscus rosa sinensis petals significantly reduced serum glucose and glycated hemoglobin levels in diabetic rats, showing effects comparable to the standard drug metformin.

In this study, administering varying doses of Hibiscus rosa-sinensis leaf water extract to BALB/c mice for 28 days did not result in significant changes in haematological parameters, body weight, or food consumption, suggesting no noticeable toxicity effects in the tested conditions.

This study found that the combination of cyproterone acetate and ethinyl estradiol improved hirsutism and acne in women, with SH 8.1041 showing significant results and both treatments being generally well-tolerated.

In this study, researchers evaluated hirsutism in young females aged 18-24 using the modified Ferriman-Gallwey scoring system, finding that 52% showed mild to moderate-to-severe symptoms, often linked to menstrual irregularities and underlying endocrine disorders like polycystic ovary syndrome and thyroid issues.

This study found that adalimumab treatment led to regression of lesions in two patients with hidradenitis suppurativa after 16 weeks of therapy.

This article provides an endocrine perspective on evaluating and managing hirsutism but reports no new research findings.

This study found that knockout mice lacking intestinal hephaestin are smaller and anemic compared to wild-type, suggesting other mechanisms may compensate for iron absorption.

This article provides guidelines for molecular genetic testing of congenital adrenal hyperplasia due to 21-hydroxylase deficiency, focusing on quality requirements, methodologies, and variant classification; it reports no new clinical results.

This study found that individualized GAHT regimens, including microdosing, effectively improved gender congruence and quality of life for non-binary individuals, but some experienced a decrease in bone mineral density.

This review provides an overview of the hairless gene in mice and humans, discussing its structure, expression, and implications for understanding skin physiology and human disorders related to gene disruption, but it reports no new empirical findings.

During LIFEHOUSE, researchers documented distinct patterns of physical exam findings and biomarker abnormalities in 369 adult employees, which may aid clinicians in recognizing wellness challenges and preventing chronic diseases associated with aging.

This article reviews possible pathogenesis scenarios for hidradenitis suppurativa and emphasizes the need for focused research on the innate immune system of hair follicles to better understand the disease.

This review discusses the physiology of hair growth, common abnormal patterns of hirsutism, and examines differential diagnoses and treatment options, but provides no new clinical findings.

This review highlights that pharmacologic therapy for hirsutism can effectively decrease hair growth, normalize menstrual cycles, and reduce endometrial cancer risk, with improvements in physical and mental well-being and minimal serious side effects reported.

This review discusses the role of heparan sulfate proteoglycans in regulating stem cell fate and highlights their potential as targets for addressing hair loss, without reporting new clinical results.

This article presents an overview of uncombable hair syndrome, emphasizing its clinical and molecular characteristics and noting systemic manifestations such as neuropsychiatric, ophthalmic, and cardiopulmonary issues.

This review discusses the hedgehog signaling pathway's role in cutaneous tumors and hematological disorders, highlighting its potential as a therapeutic target, but reports no new clinical findings.

This study found that the quality of life in Turkish women with hirsutism is significantly more affected when PCOS is present, but is not correlated with the hirsutism severity score.

Human hair follicles have their own thyroid hormone system.

This study found that a 10% carbamide peroxide solution significantly reduced acne lesions more effectively than a vehicle solution, suggesting it as a safe and effective alternative to benzoyl peroxide for treating mild to moderate acne.

This article reviews approaches to managing hirsutism but does not report new clinical findings.

This article reports on a Consent Agreement by the New York State Board charging Dr. Dennis Daly with professional misconduct related to unqualified and unlicensed practice.

This article discusses management strategies for hirsutism in women and provides no new clinical research results.

In this study, topical dehydroepiandrosterone (DHEA) doubled sebum production in women without systemic side effects, suggesting it may be a safe treatment for reduced sebum output related to menopause.

This study found that individuals with a recent history of suicide attempts exhibited altered DHEA hair levels, suggesting possible dysregulation of the HPA axis as a biopsychosocial feature, and recommends further investigation into hair hormones as potential markers of suicidal crisis and vulnerability.

This study found that in laboratory rats, toxic concentrations of hydrogen sulfide affected the immune system differently depending on age and immune suppression status, with notable changes in immune cell levels and phagocytosis, suggesting significant roles in age-associated pathologies.

This study found that the hairless gene in mice has a more extensive role in development than previously thought, as indicated by its expression in various tissues and associated abnormalities in hr/hr mutants.

This review discusses wound healing options after skin excision and laser treatments for hidradenitis suppurativa and reports no new clinical results.

This review discusses the psychological and social challenges of hirsutism in women and suggests that eflornithine cream may offer a small quality of life improvement for affected individuals, though with limited evidence.