This article discusses the physiology of hair growth, how to identify excessive hair growth in women, and when to refer them for further medical assessment, but reports no new clinical results.
30 citations
,
June 2016 in “Journal of Human Genetics” This study found pathogenic mutations in genes EDA, EDA1R, and EDARADD in 101 out of 124 hypohidrotic ectodermal dysplasia patients, revealing 23 novel mutations and indicating genetic variability.
7 citations
,
May 2010 in “Journal of Cutaneous Pathology” This study identified a novel locus for hereditary hypotrichosis simplex on chromosome 13q12.12~12.3 in a four-generation Chinese family.
March 2023 in “Journal of Drugs in Dermatology” This paper reviews the role of various hormonal therapies in treating hidradenitis suppurativa and does not report new clinical results.
10 citations
,
June 2024 in “American Journal of Clinical Dermatology” This review highlights that while sonidegib and vismodegib offer promising treatment options for advanced basal cell carcinoma, their use is often limited by treatment-emergent adverse events, which can be managed through protocol modifications and supportive interventions.
2 citations
,
January 2020 in “Evidence-based Complementary and Alternative Medicine” This study found that Hataedock may alleviate atopic dermatitis symptoms in mice by maintaining skin homeostasis and improving skin barrier formation through the endocannabinoid system.
48 citations
,
April 2015 in “PLOS ONE” In this study, hirsutism was found to have the most significant negative impact on health-related quality of life among Iranian women with polycystic ovary syndrome.
1 citations
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April 2008 in “Experimental Dermatology” This paper reviews hidradenitis suppurativa, comparing its clinical and histopathological characteristics to acne, questioning the proposed link to terminal hair follicles, and reports no new results.
112 citations
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January 2013 in “Experimental dermatology” This article offers a viewpoint on hidradenitis suppurativa pathogenesis, suggesting that impaired Notch signalling from γ-secretase mutations may drive inflammation and link the condition to other Th17-driven diseases.
28 citations
,
March 2000 in “Obstetrics and gynecology clinics of North America” This article reviews hirsutism in adolescent females, discussing its hormonal basis, potential underlying conditions, and the availability of effective therapies, without reporting new research findings.
24 citations
,
January 2017 in “Dermatology online journal” This review examines hormonal therapies, including finasteride, dutasteride, spironolactone, and oral contraceptives, for treating hidradenitis suppurativa, summarizing various clinical study outcomes but reporting no new clinical results.
September 1978 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” This review discusses the antimicrobial and protective effects of hesperidin and hesperetin against various toxicities, with potential mechanisms explored, but it reports no new research findings.
11 citations
,
November 2015 in “Journal of Functional Foods” This study found that the ethyl acetate fraction of Hibiscus rosa sinensis petals significantly reduced serum glucose and glycated hemoglobin levels in diabetic rats, with effects comparable to metformin.
June 2014 in “Toxicologie analytique et clinique/Annales de toxicologie analytique” In this study, researchers found that while chest hair can be a reliable alternative to scalp hair for ethylglucuronide testing, seasonal factors may affect concentration levels and should be considered in result interpretation.
May 2011 in “International Society of Hair Restoration Surgery” This notice from the Surgical Assistants Program Chair shares details about the September 2011 ISHRS meeting in Anchorage but reports no new research findings.
3 citations
,
September 2013 in “Journal of the American Academy of Dermatology” This report details two patients with Hutchinson-Gilford Progeria syndrome who exhibited generalized shiny skin in infancy and had a novel mutation in the LMNA gene.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that in hidradenitis suppurativa, the proteins SERPINB3/B4 and S100A7/A8/A9 were significantly overexpressed in lesional skin compared to nonlesional skin, suggesting new pathways in the disease's pathogenesis.
10 citations
,
January 2003 in “Seminars in reproductive medicine” This review covers the pathophysiology, diagnosis, evaluation, and treatment of hirsutism and reports no new clinical findings.
296 citations
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October 2018 in “General and Comparative Endocrinology” This review discusses the use of hair cortisol concentration as a marker for chronic stress and long-term cortisol secretion in animals, highlighting its benefits and the need for standardized sampling protocols.
January 2025 in “JCEM Case Reports” This report describes a 27-year-old patient with Ehler-Danlos syndrome who also presented with hypophosphatasia and mastocytosis, and suggests enzyme replacement therapy might alleviate symptoms in such overlapping genetic conditions.
February 2023 in “Archives of Dermatological Research” This study found that despite challenges, a combination of oral antibiotics, anti-androgens, oral retinoids, biologics, and surgery were important in managing hidradenitis suppurativa in patients with intellectual and developmental disabilities.
November 2010 in “Value in Health” Treating chronic hand eczema costs about the same in statutory and occupational health insurances in Germany, but work-related cases may lead to higher indirect costs due to longer work absences.
378 citations
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November 2011 in “Human reproduction update” This review discusses the epidemiology, causes, diagnosis, and management of hirsutism in women, noting that effective treatment requires addressing the root cause as well as the hair growth.
1 citations
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February 2018 in “Journal of Plastic Reconstructive and Aesthetic Surgery” This review from the 2013 Keogh Review found that non-surgical cosmetic interventions in the UK are largely unregulated, leaving patients with little protection or recourse.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated a herbal mehendi gel formulated for natural hair coloring and scalp care, finding it safe for topical use and demonstrating benefits like natural coloring and scalp conditioning.
October 2018 in “Exercise Biochemistry Review” In this mouse study, aerobic exercise was found to protect the intestinal mucosal barrier in obstructive jaundice by inhibiting the HMGB1 / TLR4 / NF-κB signaling pathway through the H2S / CSE system.
354 citations
,
August 1991 in “Molecular Endocrinology” This study found that distinct isoenzymes of 3 beta-hydroxysteroid dehydrogenase are expressed in human adrenals and gonads compared to the placenta and skin.
January 2022 in “SSRN Electronic Journal” This submission discusses the updated CPSO policy on human rights in healthcare, suggesting it imposes excessive requirements on physicians objecting to certain services for ethical reasons, and recommends a unified protection of conscience policy.
2 citations
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June 2020 in “Clinical & experimental allergy/Clinical and experimental allergy” This study found that the implementation of a streamlined referral pathway improved the rate of anaphylaxis referrals from an emergency department to a specialized allergy service from 0% in 2007 to 44% in 2016.
January 2015 in “Side effects of drugs annual” This review discusses various sex hormones and related compounds, including estrogens and anabolic steroids, but reports no new findings; it highlights existing literature from 2014 regarding their use and effects.