Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the physiology of hair growth, common abnormal patterns of hirsutism, and examines differential diagnoses and treatment options, but provides no new clinical findings.

This publication provides a standardized nomenclature for classifying microscopic lesions in laboratory rat and mouse skin, aiming to harmonize international toxicological research.

This study found that DHHC13 is crucial for hair anchoring and skin barrier function, with its deficiency in Zdhhc13(skc4) mice leading to cyclic alopecia and skin abnormalities due to cornifelin deficiencies.

This study reports that actively proliferating Lgr5+ stem cells in hair follicles do not appear to drive tumor formation in experimental skin carcinogenesis.

This narrative review highlights the potential of naturally occurring compounds to target specific molecular pathways and overcome resistance in advanced and recurrent papillary thyroid cancer, offering new therapeutic possibilities beyond traditional treatments like surgery and lifelong hormone replacement.

This review discusses the etiology, diagnosis, and management strategies for hirsutism, noting that serious underlying disorders are rare and emphasizing targeted treatment to manage testosterone's effects.

This study found that the loss of a functional hr gene in mice leads to premature and abnormal hair follicle regression, disrupting normal hair cycling and architecture.

The document explains that hirsutism, often caused by hormonal issues, can be managed with treatment to improve both physical appearance and mental health.

This study observed that among Iraqi women with hirsutism, most had hypothyroidism and elevated hormone levels, particularly DHEAS and testosterone, with acne being the most common associated clinical feature.

This study found that polycystic ovary syndrome is the most common cause of hirsutism in premenopausal Algerian women, with recommendations for thorough endocrinologic evaluations.

This study found that Hairless (Hr) acts as a corepressor of the vitamin D receptor (VDR) in human keratinocytes, blocking the action of vitamin D on keratinocyte differentiation.

This study identified the Hairless (Hr) gene-encoded protein as a corepressor that plays a crucial role in maintaining skin and hair by regulating epithelial stem cell differentiation and gene expression via chromatin remodeling, which may impact both development and disease.

This review discusses causes and treatments for hirsutism in women and reports no new clinical results.

This narrative review discusses various causes and treatments of hirsutism in women, emphasizing the importance of identifying androgen-secreting tumors, but does not present new study results.

This study conducted physical examinations on fifty women with hirsutism, focusing on virilization signs, but reports no new clinical findings.

This article discusses the causes of hirsutism, identifying increased androgen production and heightened skin sensitivity, and provides no new clinical results.

Lasers are effective for hair removal, especially for conditions like excessive hair growth.

This study found that a newly identified mutation in the hairless gene in mice led to decreased Hr mRNA levels and changes in gene expression related to hair follicle development.

This study found that the clionasterol-rich hexane fraction of Caulerpa racemosa may protect against particulate matter-induced skin damage by reducing oxidative stress and mitochondrial-mediated apoptosis in human keratinocytes and zebrafish.

In this study of premenopausal Iranian women with hirsutism, polycystic ovary syndrome was a common cause and frequently associated with menstrual irregularity, while elevated androgens or hyperandrogenic conditions were also observed.

This study suggests that the HCR risk allele within the PSORS1 locus may contribute to psoriasis susceptibility by altering gene expression related to skin structure and differentiation, although these changes alone might not result in clinical symptoms.

This study found that GnRH-A treatment significantly reduced hirsuties scores in women with mild idiopathic hirsuties but did not affect hair growth rate or diameter.

This study found that hirsute women had a significantly higher incidence of psychological issues compared to controls, unrelated to the severity of their hirsutism or androgen levels.

This study identified complex regulatory elements and interactions involving the Hr gene and HR protein that are crucial for hair follicle formation and cycling in mammals.

This review discusses existing and emerging treatments for hirsutism, highlighting new home-use laser devices, and reports no new clinical results; the authors note that permanent hair removal remains elusive.

In this study, researchers identified a novel and two previously reported pathogenic mutations in the HR gene associated with atrichia with papular lesions in five Pakistani families.

This study found that mutations in exon 3 of the hr gene are strongly associated with congenital hypotrichosis in Valle del Belice sheep, suggesting a potential genetic link to the disorder.

This study compared hirsutism levels, hand measurements, testosterone, and DHEAS levels in women aged 18 to 38 but does not report new definitive findings.

This article reviews the assessment, causes, and management approaches for hirsutism in women, emphasizing ethical considerations concerning unapproved drug use and contraceptive responsibility but reports no new clinical findings.

This report presents the first documented case of CARASIL in an Arabic patient and notes unique magnetic resonance spectroscopy findings compared to prior cases.