April 2020 in “Journal of the Endocrine Society” This case report describes a 34-year-old woman with pituitary stalk interruption syndrome, highlighting the need for long-term follow-up due to potential progression from isolated hormonal deficiencies to pan-hypopituitarism.
2 citations
,
June 2021 in “RECERCAT (Consorci de Serveis Universitaris de Catalunya)” Clear definitions and strategies are needed to manage long-term COVID-19 symptoms effectively.
March 2011 in “Open Archive (Karolinska Institutet)” This study explored the effects of a common Hutchinson-Gilford progeria syndrome mutation in an inducible mouse model, revealing skin abnormalities similar to those in affected patients.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This case study details a 26-year-old woman diagnosed with PCOS and metabolic syndrome, highlighting the importance of early recognition and multidisciplinary management to improve reproductive and metabolic health outcomes.
51 citations
,
February 2004 in “Journal of Investigative Dermatology” MCSP may help identify and regulate skin stem cells, affecting hair growth and regeneration.
1 citations
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July 2007 in “Journal of Investigative Dermatology” The mutation causes hairless mice due to mislocalized and dysfunctional HR protein.
March 2023 in “Cellular Molecular and Biomedical Reports” The researchers reported that lifestyle changes and medications significantly impact managing PCOS, highlighting the high prevalence of cardiovascular comorbidities and the common risk factor of high BMI in these patients.
January 2023 in “International journal of homoeopathic sciences” This study collected data on PCOS symptoms among female students and assessed the prevalence of menstrual irregularities, obesity, hirsutism, alopecia, and severe acne in this group.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This case presentation highlights a 26-year-old woman with PCOS, metabolic syndrome, and prediabetes, emphasizing the importance of early recognition and multidisciplinary management to prevent long-term metabolic complications.
January 2025 in “Clinical Case Reports” This case study details the successful treatment of macrophage activation syndrome with dexamethasone and cyclosporine in a 36-year-old woman with adult-onset Still's disease, highlighting the critical importance of timely aggressive treatment.
January 2018 in “Deleted Journal” In this observational study of 110 women with PCOS, the researchers found that 52.7% experienced depression and anxiety, with Metformin being the most prescribed drug. Regular counseling and lifestyle management were noted to improve the overall disease prognosis.
28 citations
,
October 2013 in “Journal of The American Academy of Dermatology” In this study, ovarian SAHA was found to be independently associated with a more insulin-resistant profile and increased risk of glucose abnormalities in women with PCOS, beyond common risk factors.
85 citations
,
June 2008 in “Annals of the New York Academy of Sciences” This article proposes a hypothesis that hyperandrogenemia is the final common pathway for developing adolescent PCOS and emphasizes the importance of reducing androgen levels to mitigate risks of metabolic syndrome, diabetes, and infertility in adulthood.
August 2025 in “Journal of Medical and Life Science” This case-control study in Missan Province, Iraq, found that married women with PCOS had higher rates of obesity and menstrual irregularities, along with elevated testosterone, LH, and insulin levels, compared to healthy controls, highlighting significant hormonal and metabolic complications.
April 2008 in “Obstetrics, gynaecology and reproductive medicine” This article reviews the diagnosis and management of hirsutism in women, discussing its causes, assessment, and treatment options; no new clinical findings are included.
September 2017 in “Fertility and sterility” This study observed that among Vietnamese women with PCOS, waist circumference was greater and hirsutism occurred more on non-facial sites compared to non-PCOS infertility controls.
January 2015 in “Springer eBooks” This chapter reviews polycystic ovary syndrome's clinical features, highlighting diagnostic criteria and management strategies, and reports no new findings; the authors emphasize the need for targeted treatment approaches.
March 2024 in “Journal of Rawalpindi Medical College/Journal Rawalpindi Medical College” This study observed that skin conditions like hirsutism, acne, and androgenic alopecia were common in PCOS patients and may aid in its diagnosis.
7 citations
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December 2014 in “Gynecological Endocrinology” This study found that LC-MS/MS is a more reliable method than immunoassays for measuring serum 17OHP and androgen levels in women with hyperandrogenism.
August 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This article discusses how activating the hexosamine pathway may enhance skin homeostasis by increasing hyaluronic acid secretion and supporting hair follicle stem cell self-renewal, but reports no new results.
9 citations
,
January 2015 in “Springer eBooks” This article reviews the diagnostic criteria and management strategies for polycystic ovary syndrome but reports no new clinical findings; it highlights associated health risks and recommended treatments.
7 citations
,
January 1992 in “Adolescent and pediatric gynecology” This review discusses the unique challenges of diagnosing and managing polycystic ovarian syndrome in adolescents and reports no new clinical findings.
2 citations
,
January 2014 in “Case Reports in Clinical Medicine” This case study presents an 81-year-old woman diagnosed with Cronkhite-Canada syndrome and discusses the importance of recognizing its clinical and histopathological features for timely and accurate diagnosis.
11 citations
,
December 2013 in “Clinical and experimental dermatology” This study reports a case of a child with congenital skin fragility, alopecia, and cardiomyopathy due to compound heterozygous mutations in the DSP gene causing desmoplakin deficiency.
48 citations
,
April 2015 in “PLOS ONE” In this study, hirsutism was found to have the most significant negative impact on health-related quality of life among Iranian women with polycystic ovary syndrome.
119 citations
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November 2016 in “American journal of human genetics” This study reports the discovery of mutations in the PADI3, TGM3, and TCHH genes as molecular genetic causes of uncombable hair syndrome in children, indicating an autosomal-recessive inheritance pattern.
June 2026 in “International Journal of Reproduction Contraception Obstetrics and Gynecology” This study found that serum Anti-mullerian hormone (AMH) levels are significantly elevated in women with polycystic ovary syndrome and can serve as a useful biomarker for diagnosis, especially when ultrasonography is unavailable.
1 citations
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November 2016 in “Frontiers in neurology” In this case report, a patient with Cronkhite-Canada syndrome also had mononeuritis multiplex, and the authors suggest that an autoimmune mechanism may be involved based on steroid responsiveness and electrophysiological findings.
2 citations
,
October 2019 in “The Egyptian Journal of Hospital Medicine” This study found that anti-Müllerian hormone (AMH) showed high sensitivity and specificity as a diagnostic marker for polycystic ovary syndrome in the studied population, suggesting its promise as an objective diagnostic tool.
This review outlines acne management strategies for individuals with polycystic ovary syndrome, but reports no new clinical results.