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The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Metformin effectively improves metabolic symptoms in women with PCOS, while alfacalcidiol does not have a significant impact.

The medication combination did not affect glucose tolerance but increased some cholesterol levels due to its estrogen component.

Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

Existing drugs are being repurposed to treat cardiometabolic disorders, which is safer, faster, and cheaper than developing new drugs.

The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.

Minoxidil works better for female hair loss, but cyproterone reduces scalp oiliness and causes menstrual issues.

Researchers developed a method to detect hormone-blocking drugs in wastewater and found them in Beijing's sewage, suggesting they can survive sewage treatment.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.

About 15% of US Army personnel use hair products containing hormone or placenta, with higher usage among non-whites, females, and enlisted personnel.

Finasteride helps prevent kidney stones, but side effects need more research.

PTHRP agonists can stimulate hair growth, especially in damaged follicles, while antagonists may initially increase growth but ultimately inhibit it.

Women with PCOS have lower adiponectin hormone levels and are more likely to have insulin resistance.

Teprotumumab for thyroid eye disease commonly causes fatigue, brittle nails, dry eyes, hair loss, muscle spasms, and dry mouth, with rare serious events like blood clots.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Voriconazole can cause serious side effects, especially in long-term use.

Lower SHBG levels may increase the risk of PCOS.

Some common medications can harm male fertility, but many effects can be reversed.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Antidepressants called SSRIs can cause skin problems, bleeding risk, and other side effects.

Hormone therapy for excessive hair growth is as good with GnRHa as with high-dose CPA, but GnRHa has longer-lasting results.

Melatonin may help treat PCOS symptoms in rats.

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.