Literature Review: Nutrafol vs. Microinflammation

The 2018 literature review discussed the potential benefits of Nutrafol, a hair supplement containing various botanical ingredients, in treating hair loss. Nutrafol includes curcumin, an anti-inflammatory and free radical scavenger, which also inhibits transcription factor TNF-kB and has natural anti-androgen effects. To improve curcumin's typically poor absorption, it is co-administered with black pepper. Other ingredients include Ashwaghandha, an adaptogen known for lowering stress cortisol levels, and Saw palmetto, a natural plant-based 5-AR inhibitor. The supplement also contains tocopherols and marine-based collagen hydrolysates. The review suggested that these supplements could help mitigate inflammatory factors contributing to hair loss. However, the review also noted the lack of placebo-controlled clinical studies confirming the efficacy of Nutrafol, indicating that more data was needed.