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Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.

Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

New treatments for hair loss are being developed using molecular biology.

Future hormone therapy trials should match the diverse needs and priorities of the gender-diverse community.

Young women with diffuse hair loss may have low SHBG levels, which could lead to more active testosterone and contribute to their hair loss.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Transfollicular drug delivery is promising but needs more research to improve and understand it better.

Ayurvedic herbs may reduce side effects and improve effectiveness of cancer treatments.

No cure exists for alopecia areata, and treatments are personalized.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Melatonin and mitotane treatment led to hair re-growth in 62% of dogs with Alopecia X, but this was not always linked to normal hormone levels.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.

Clinicians should use social and prescription data to track trends in performance-enhancing drug use.

Phthirusa pyrifolia extract may lower testosterone and harm male rat reproduction without damaging the liver or kidneys.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Certain drugs that block specific enzymes can help treat prostate diseases.

Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.

Non-drug methods like diet, supplements, and aromatherapy can help manage hair loss and its emotional impact.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.