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Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.

Oxidative stress affects hair loss in men with androgenetic alopecia.

Changes in the HR gene have influenced hair growth and may lead to hair loss conditions in humans.

Women with PCOS often have metabolic issues like insulin resistance and a higher risk of diabetes and abnormal lipid levels.

Women with PCOS often have insulin resistance, abnormal lipid levels, and a higher risk of diabetes and heart disease; lifestyle changes and medication like metformin can help manage these risks.

Some women with PCOS have rare genetic variants linked to the condition.

Testosterone and its metabolites have varied effects on different body systems, especially during puberty.

Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Omega-6 fats in certain cells boost male hormone production.

Cattle skin has leptin which might control skin and hair growth.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

The GH-IGF-I axis is likely involved in the hormonal imbalances seen in non-obese women with functional hyperandrogenism.

Regulating certain sex hormones may help delay facial aging.

Adrenal glands delay the start of winter fur growth in mink.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Finasteride effectively treats BPH but may increase sexual dysfunction risk.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

RU58841, a nonsteroidal anti-androgen, showed potential as a topical treatment for hair loss, increasing hair density, thickness, and length without systemic side effects in Stumptailed Macaques.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.