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The unique coat of lykoi cats is likely caused by new variants in the Hairless gene.

Asiasari radix extract may be a potential treatment for melanoma because it selectively triggers cell death in melanoma cells by affecting p53 regulation.

Nuclear shape and chromatin changes affect gene expression in skin cell differentiation.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.

Innovative methods are reducing animal testing and improving biomedical research.

Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.

The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Our microbiome may affect the development of the hair loss condition Alopecia Areata, but more research is needed to understand this relationship.

Polycystic ovary syndrome and iron overload share similar symptoms and can be potentially treated with blood removal, diet changes, and probiotics.

Drug repurposing speeds up drug development, saves money, and has led to about a third of new drug approvals.

The Notch signaling pathway is important for hair follicle development and could help create treatments for hair disorders.

The circadian clock plays a key role in hair growth and its disruption can affect hair regeneration.

The study suggests that higher levels of SIRT1 and SIRT2 may improve overall cell health and aging processes.

Nrf2 helps protect skin from damage but too much can cause skin problems.

Some treatments can improve skin's defense against damage, but overuse may cause other skin problems.

Zinc can help with some skin problems, but its effectiveness varies depending on the condition.

Topical therapies show promise for hair loss and acne treatment with minimal side effects.

Antioxidants may help improve mitochondrial health and could be used to treat diseases related to cell damage.

The document concludes that the discussed biological mechanisms and potential therapies are not related to hair loss or hair growth.

Metabolism plays a key role in determining stem cell fate.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Sodium valproate is effective in treating epilepsy, especially in patients who don't respond to other medications.

Acid inside cells speeds up aging and turns on aging signs in mice.

Six new hair loss factors in men not linked to female hair loss.

DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.