358 citations,
January 1968 in “Physiological Reviews” Histamine plays key roles in immune responses, stomach acid, and brain signals.
170 citations,
December 2009 in “Histopathology” The conclusion is that accurate diagnosis of different types of hair loss requires good teamwork between skin doctors and lab experts.
142 citations,
March 2019 in “Frontiers in Cellular Neuroscience” The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.
122 citations,
April 1995 in “Journal of Cutaneous Pathology” The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.
97 citations,
May 2008 in “Journal of Cutaneous Pathology” Different soft tissue fillers can cause various skin reactions; biodegradable fillers are safer and non-biodegradable ones like silicone can lead to long-term problems.
95 citations,
January 2004 in “Archives of Dermatological Research” Peripilar signs can help diagnose androgenetic alopecia and reveal its cause.
90 citations,
June 2006 in “The American Journal of Dermatopathology” The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.
74 citations,
July 2008 in “Dermatologic therapy” Early detection and histopathology are crucial to prevent permanent hair loss in cicatricial alopecia.
74 citations,
November 2000 in “Archives of Dermatology” Salicylic acid can safely exfoliate and regenerate skin without causing inflammation.
73 citations,
November 2001 in “Journal of Investigative Dermatology Symposium Proceedings” Markers help differentiate between apocrine and eccrine sweat glands to identify sweat gland tumors.
57 citations,
August 1997 in “Microscopy Research and Technique” New molecules involved in skin and hair growth were identified, improving understanding and future treatments.
54 citations,
January 2018 in “Scientific reports” Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.
53 citations,
February 2017 in “Journal of The American Academy of Dermatology” The conclusion is that high-potency steroids or tacrolimus are effective treatments for erosive pustular dermatosis of the scalp.
53 citations,
September 2011 Other common signs, not just the well-known immune cells around hair bulbs, are important for diagnosing hair loss from alopecia areata.
43 citations,
May 2011 in “Dermatologic Therapy” Recognizing the different stages of alopecia areata is crucial for accurate diagnosis and treatment.
42 citations,
July 2015 in “Drug Development and Industrial Pharmacy” Flutamide, delivered by solid lipid nanoparticles, could potentially treat hair loss.
39 citations,
May 2019 in “Journal of the American Academy of Dermatology” Hair loss in lupus patients indicates higher disease activity.
38 citations,
October 1988 in “Clinics in Dermatology” Minoxidil can help grow hair and make hair follicles bigger, but it can also cause side effects.
34 citations,
January 2005 in “Journal of the American Veterinary Medical Association” Cyclosporine A can reduce inflammation in dogs with sebaceous adenitis, but ongoing treatment is needed.
34 citations,
February 2012 in “Journal of Cutaneous Pathology” The research found specific signs to diagnose alopecia areata incognito and noted patients generally regrow hair after steroid treatment.
32 citations,
June 2013 in “Journal of Investigative Dermatology” Mice without certain skin proteins had abnormal skin and hair development.
31 citations,
April 2019 in “Journal of Cutaneous Pathology” Hair becomes gray and thin as we age, and while most hair loss in older people is due to genetics, there's a chance for gray hair to regain color under certain conditions.
31 citations,
April 2016 in “Nature communications” Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.
31 citations,
August 2005 in “The American Journal of Dermatopathology” The study concluded that PKP1 is essential for skin integrity and hair growth, and its dysfunction causes the symptoms of ectodermal dysplasia/skin fragility syndrome.
29 citations,
October 2012 in “Anais Brasileiros De Dermatologia” Diagnosing hair loss disorders needs clinical, dermoscopic, and histological differences, and checking menstrual cycle, weight changes, drug therapy, and nail changes.
28 citations,
March 2010 in “Clinics in dermatology” Doctors have known about fungal skin infections for a long time, but only made major progress in understanding and treating them since the mid-1800s.
27 citations,
August 2014 in “Journal of Cosmetic and Laser Therapy” Different lasers and radiofrequency affect skin differently, important for dermatologists to choose the right treatment.
26 citations,
January 2002 in “Advances in experimental medicine and biology” Finasteride, originally for prostate issues, also treats hair loss, similar to effects from certain plants.
25 citations,
August 1992 in “In vitro cellular & developmental biology” The new system can grow hair in the lab and test hair growth treatments.
22 citations,
June 2017 in “Advances in Clinical and Experimental Medicine” Polycystic ovary syndrome (PCOS) was first described in 1721, officially diagnosed in the 1990s, and is now known to be partly genetic and linked to insulin resistance, with increased risk of cardiovascular disease and carbohydrate metabolism issues.