77 citations
,
May 2012 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are effective and should be personalized.
16 citations
,
November 1992 in “Journal of International Medical Research” In this randomized study, ViviScal® significantly outperformed a fish extract in increasing non-vellus hair count and achieving clinical and histological improvement in young males with hereditary androgenic alopecia.
51 citations
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October 2002 in “European journal of endocrinology” This study found that both high-dose and low-dose finasteride significantly reduced hirsutism scores in women after 12 months, with the lower dose being safe and cost-effective.
June 2023 in “JAAD international” This report highlights that 49.4% of U.S. patients with skin issues use complementary and alternative medicine (CAM), with 6% leveraging it specifically for their skin conditions, including treatments like herbal, vitamin, and mineral supplementation for alopecia.
19 citations
,
March 2018 in “JAMA” This guideline discusses the evaluation and treatment of hirsutism in premenopausal women, recommending oral contraceptive pills or antiandrogens as initial therapies with weak support from low-quality evidence.
July 2025 in “International Journal of Research in Dermatology” This survey found that healthcare professionals view a novel nutritional supplement containing a natural DHT inhibitor as a beneficial adjuvant in the treatment of androgenetic alopecia among Indians.
8 citations
,
June 2016 in “PubMed” This review discusses the use of finasteride for treating hidradenitis suppurativa and reports favorable outcomes in several cases, suggesting it could be an effective and safe option for certain patients.
28 citations
,
May 1986 in “Clinics in endocrinology and metabolism” This review discusses the potential of 4-azasteroids as 5α-reductase inhibitors for treating hirsutism, reporting their promising effects in animal studies but noting no clinical trials have been conducted yet.
January 2018 in “Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment” This study developed and validated a method using UPLC-PDA and LC-Q-TOF/MS to identify and measure prohibited substances in dietary supplements, showing reliable detection of compounds like minoxidil and finasteride.
March 2024 in “CRC Press eBooks” This chapter reviews hormonal imbalances and related disorders, discussing nutraceuticals—such as cod liver oil, green tea, and Omega-3s—that may alleviate symptoms and improve hormonal fluxes in lieu of traditional synthetic treatments that have potential side effects.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, the researchers introduced the Keyora Lycopene 23 in 1 formulation, demonstrating its potential to improve male endocrine and reproductive health by addressing oxidative stress, nitric oxide deficiency, androgen imbalance, and mitochondrial dysfunction through a comprehensive multi-nutrient approach.
March 2023 in “Journal of Drugs in Dermatology” This paper reviews the role of various hormonal therapies in treating hidradenitis suppurativa and does not report new clinical results.
4 citations
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July 2023 in “Journal of Drugs in Dermatology” This review analyzed past research on hormonal treatments for hidradenitis suppurativa, finding that anti-androgens like finasteride and spironolactone, along with metformin, showed promise but large-scale trials are needed to understand their full potential.
32 citations
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August 1985 in “Clinical endocrinology” This study concluded that spironolactone may be an effective therapy for a subgroup of hirsute patients, as it reduced plasma testosterone and improved certain hair growth measures.
64 citations
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January 1985 in “Clinical endocrinology” In this study, treatment with the oral contraceptive containing 30 μg ethinyl oestradiol and 150 μg desogestrel significantly reduced androgen-dependent hair growth in hirsute women over one year.
December 2000 in “Journal of the Royal Society of Medicine” Antiandrogen therapy may help treat hidradenitis suppurativa.
14 citations
,
June 2014 in “World Journal of Urology” This study found that the herbal combination PRO 160/120 significantly improved nocturnal voiding frequency in patients with moderate-to-severe LUTS/BPH compared to placebo, with similar effectiveness to tamsulosin and finasteride.
40 citations
,
May 2018 in “PubMed” In this randomized, double-blind, placebo-controlled study, daily use of the Nutrafol® Women's Capsules nutraceutical significantly increased the number of terminal and vellus hairs and improved hair quality in women with self-perceived thinning over six months, without any reported adverse events.
29 citations
,
April 2004 in “Annals of Pharmacotherapy” This review concluded that finasteride may reduce hirsutism scores and hair diameter in women with hyperandrogenism, but concerns about teratogenicity and long-term safety make it a secondary treatment option.
This study found that applying amaranthus extract cream to the scalp significantly improved terminal hair density, anagen hair count, and pilary index in men with male pattern hair loss, suggesting it may be a safe and effective supportive therapy.
January 1993 in “Inpharma Weekly” A new food supplement was highly effective in curing hair loss in young men.
6 citations
,
November 2015 in “JAMA” This study found that oral contraceptive pills improve mild hirsutism, while flutamide and spironolactone are beneficial for more severe cases, but other therapies show inconsistent or no benefit.
14 citations
,
March 2010 in “Gynecological endocrinology” This article provides an overview of treatment options for hirsutism, summarizing both pharmacologic and non-pharmacologic approaches, but reports no new clinical results.
10 citations
,
January 2000 in “PubMed” This study found that GnRH agonist treatment improved hirsutism scores more than finasteride after six months in women with idiopathic hirsutism, with both treatments causing no menstrual abnormalities or side-effects.
56 citations
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April 2003 in “Fertility and Sterility” This study found that while cyproterone acetate, finasteride, and spironolactone had similar short-term effects in treating idiopathic hirsutism, spironolactone provided more lasting benefits one year after treatment.
14 citations
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September 2007 in “Steroids” This study suggests that androstendione and DHEA are useful indicators for diagnosing hyperandrogenemia in hirsute women, while DHEAS was not found to be helpful.
27 citations
,
July 2009 in “Experimental and Clinical Endocrinology & Diabetes” This study found that finasteride significantly improved hirsutism scores in women over 12 months and was well-tolerated with no serious side effects.
27 citations
,
January 2001 in “Endocrine Practice” In this preliminary study, women with facial hirsutism treated with topically applied finasteride cream showed a significant decrease in hair growth and thickness compared to placebo, without adverse effects.
22 citations
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August 2011 in “Endocrine Practice” This review discusses the etiology, diagnosis, and management strategies for hirsutism, noting that serious underlying disorders are rare and emphasizing targeted treatment to manage testosterone's effects.
4 citations
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January 2017 in “Innovare Academic Sciences - Innovare Journal of Business Management” This study found that several herbal extracts, like those from Tridax procumbens and Ginko biloba, have demonstrated hair growth-promoting effects in both animal models and in vitro experiments.