April 2025 in “Al-Azhar International Medical Journal /Al-Azhar International Medical Journal” This study found that topical minoxidil 5% remains the most common treatment for androgenic alopecia due to its high tolerability and patient satisfaction, but topical sildenafil 2% shows promise as an alternative, especially with positive hair thickness outcomes in certain areas.
April 2025 in “The Obstetrician & Gynaecologist” This study highlights that hirsutism in women, most commonly caused by polycystic ovary syndrome, should be evaluated with tools like the Ferriman–Gallwey score and total testosterone measurements, and managed using methods like hair removal and combined oral contraceptives when fertility preservation is not a priority.
June 1993 in “Current opinion in therapeutic patents” This study reports that novel hexahydrobenzoquinolin compounds fully inhibited 5α-reductase activity in human genital skin fibroblasts, suggesting their potential for treating conditions like benign prostatic hyperplasia and male pattern baldness.
20 citations
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September 1987 in “The Lancet” April 2026 in “Journal of Natural Remedies” This review presents a comprehensive evaluation of eleven traditional herbs, detailing their phytochemical properties, mechanisms, pharmacokinetics, and potential roles in managing alopecia, positioning them as holistic alternatives to conventional treatments like minoxidil and finasteride.
30 citations
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April 1997 in “European journal of endocrinology” The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.
September 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study introduces the MHS Hair Restoration Protocol, a systems-biology model targeting hair follicle health through the gut-microbiome-endocannabinoidome axis and innovative topical treatments, emphasizing a holistic approach to pattern hair loss.
6 citations
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June 2014 in “PubMed” This study concluded that transurethral seminal vesiculoscopy combined with finasteride is a safe and effective treatment for recurrent hemospermia in the observed patients.
This study concluded that adding a topical agent to intense pulsed light therapy significantly improved hair reduction and patient satisfaction in Pakistani women with idiopathic facial hirsutism compared to light therapy alone, without increasing adverse effects.
1 citations
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October 1997 in “PubMed” This study found that both finasteride and flutamide significantly decreased hirsutism severity and hair diameter in women with PCOS and Idiopathic Hirsutism, with abdominal hairs showing greater sensitivity to the treatments.
September 2021 in “Conference Proceedings” This study observed that hyperandrogenism in men manifests with varying symptoms, where older men may have high total testosterone due to increased SHBG without elevated free testosterone, while younger men often show signs like acne and alopecia with elevated DHT or testosterone.
November 2020 in “Journal of the American Academy of Dermatology” Intense pulsed light with radiofrequency showed mixed results in improving quality of life for hidradenitis suppurativa patients, with no clinical improvements.
November 2014 in “PubMed”
April 2011 in “Global journal of health science” This study found that spironolactone alone or with oral contraceptive pills significantly reduced hair shaft diameter in women with hirsutism, with the greatest reduction observed for the combination treatment.
May 2008 in “10th European Congress of Endocrinology” Flutamide alone is as effective as the combination with finasteride for treating hirsutism.
July 2026 in “Journal of the American Academy of Dermatology” 19 citations
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May 2020 in “American journal of men's health” This review discusses androgen therapy in adolescents, detailing current practices and noting the limited use of commercially available testosterone or dihydrotestosterone formulations; no new results are reported.
1 citations
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January 2016 in “Journal of Advanced Plastic Surgery Research” This study found that the LightSheer Diode EP Laser System significantly reduced hair growth among women with hirsutism, with side effects disappearing within three days and no long-term skin pigmentation issues observed.
50 citations
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May 2000 in “Fertility and Sterility” This study found that flutamide was more effective than finasteride in reducing hair growth in women with hirsutism over a one-year period.
July 2025 in “International Society of Hair Restoration Surgery” This article discusses initiatives by the ABHRS to enhance hair restoration surgery standards but presents no new research findings.
December 2022 in “Research Square (Research Square)” In this study, a comprehensive treatment approach involving multiple therapies was found to play a crucial role in managing hidradenitis suppurativa in patients with intellectual and developmental disorders despite practical challenges.
50 citations
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July 1996 in “Fertility and Sterility” This study found that finasteride significantly reduced hirsutism scores in women with idiopathic hirsutism and PCOS, despite no changes in serum androgen levels.
The text is about acne, excessive hair growth, and hair loss due to hormones.
July 2025 in “Colloids and Surfaces B Biointerfaces” This study found that the new delivery system HL@Mi enhanced the skin penetration, local bioavailability, and safety of minoxidil, supporting improved hair growth in an androgenetic alopecia animal model.
March 2020 in “Hair transplant forum international” In this letter to the editor, researchers in Madrid discuss the effectiveness and safety of low-dose oral minoxidil for treating male androgenetic alopecia, but specific results or findings are not reported in the abstract.
80 citations
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January 1988 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study observed that high-dose spironolactone frequently caused metrorrhagia in women with idiopathic hirsutism, leading the authors to suggest lower starting doses or additional hormonal therapy.
3 citations
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January 2008 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This article reviews factors influencing hidradenitis suppurativa, its clinical diagnosis, and the diverse management approaches but presents no new clinical findings.
8 citations
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January 2021 in “Fermentation” This article discusses the potential role of probiotics and synbiotics in managing hirsutism through insulin resistance but reports no new clinical results, calling for further research.
December 2023 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Many women in Turkey have hirsutism, according to the research group's findings.
2 citations
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May 2019 in “Journal of the American Academy of Dermatology” The correspondence discusses the higher prevalence of acne vulgaris in hidradenitis suppurativa patients, but notes potential overestimation due to unrecognized facial HS.