29 citations
,
June 2017 in “Journal of Inherited Metabolic Disease” This review discusses the potential of using high-throughput and high-content screening methods for drug repositioning in rare diseases and reports no new results.
62 citations
,
March 2013 in “JAMA Dermatology” This case series reported that three pediatric patients with hidradenitis suppurativa showed decreased frequency and severity of disease flares after treatment with oral finasteride, with no significant adverse effects.
January 2026 in “Chemical Engineering Journal” In this study, researchers developed a programmable system using engineered nanovesicles from hair follicle stem cells to modulate immune responses, which showed promise in precisely controlling inflammation, promoting immune balance, and accelerating wound healing, particularly for infected wounds.
July 2025 in “Interdisciplinary materials” This study found that a microneedle patch integrating curcumin-loaded vesicles and a stem cell-derived matrix showed promise in reducing hypertrophic scars and promoting hair follicle formation in a rabbit model.
7 citations
,
May 2014 in “Iranian Red Crescent medical journal” This case study describes a 17-year-old female with severe hirsutism diagnosed with PCOS, NC-CAH, and HAIR-AN syndrome who was successfully treated based on her specific underlying conditions.
14 citations
,
June 2021 in “British journal of dermatology/British journal of dermatology, Supplement” This paper presents consensus guidelines for standardized diagnostic criteria and assessment methods for frontal fibrosing alopecia to improve clinical research and data collection globally.
1 citations
,
February 2017 in “The American journal of dermatopathology/American journal of dermatopathology” This case report presented a 52-year-old man with cutaneous focal mucinosis, exhibiting rare follicular induction of the epidermis, underscoring the importance of recognizing this association in differential diagnoses.
4 citations
,
January 2016 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that the FSHR Ser680Asn (rs6166) gene polymorphism is associated with an increased risk of PCOS in the examined population and could serve as a molecular biomarker for identifying risk.
1 citations
,
June 2024 in “Skin Research and Technology” This study found that secretory proteins in DFCM play crucial roles in regulating nerve restoration by forming significant protein interaction networks during the wound repair process.
This study found that a modified scaffold with VEGF165 genetically modified hair follicle stem cells significantly promoted blood vessel growth and wound healing in rats, suggesting its potential as a skin substitute in clinical settings.
November 2025 in “Contact Dermatitis” In this case study, a 34-year-old woman experienced facial allergic reactions to SPF-containing products, and patch tests identified sensitization to salicylates, which when avoided, stabilized her symptoms and her existing frontal fibrosing alopecia, highlighting a possible link to investigate further.
42 citations
,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” This abstract omits specific findings and does not provide new research results.
January 2026 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this study, Exosome Hypoxia Mesenchymal Stem Cells significantly reduced inflammation and promoted hair follicle regeneration by normalizing IL-1Beta and IGF-1 levels in fluconazole-induced alopecia-like Wistar rats.
39 citations
,
September 2019 in “Materials & Design” This study developed a new mask-free method using digital micromirror and microfluidic systems to create multicellular heterospheroids for drug screening, finding that heterospheroids exhibit higher drug resistance and combinatorial drugs are more effective than single drugs in cancer therapeutic applications.
16 citations
,
November 2011 in “PubMed” This study found that a single intradermal injection of Hair Stimulating Complex significantly improved hair growth in men with androgenetic alopecia compared to placebo.
October 2025 in “Journal of Investigative Dermatology” Hair follicle dermal stem cells help control hair growth timing by regulating signals at the hair germ–dermal papilla interface.
January 1982 in “Clinical Cosmetic and Investigational Dermatology” This case report describes a 54-year-old woman with familial dyskeratotic comedones who experienced slight improvement in her skin lesions after three months of treatment with topical retinoids and urea cream.
26 citations
,
December 2015 in “Journal of The European Academy of Dermatology and Venereology” This article introduces a new grading system called the FPHL Severity Index to better identify and monitor early stages of female pattern hair loss using clinical criteria.
November 2021 in “SPAST Abstracts” In this study, EFH-SLM cream demonstrated greater efficiency in reducing hair density compared to plain EFH cream in Swiss albino female mice, with significantly less skin irritation and inflammation observed, suggesting improved permeability and effectiveness of EFH when using the new cream formulation.
43 citations
,
July 2017 in “International journal of pharmaceutics” This study found that anionic HSES achieved high complexation efficiencies with various steroids, significantly enhancing their solubility, while specific β-cyclodextrin thioethers showed selective binding to testosterone and estradiol.
15 citations
,
February 2021 in “Scientific Reports” This study identified a specific subpopulation of hair follicle stem cells in mice and humans that are essential for long-term hair regeneration, highlighting the potential for regenerative therapy.
51 citations
,
March 2019 in “Experimental Dermatology” This study suggests that in hidradenitis suppurativa, MMP-induced matrix alterations may contribute to inflammation by releasing active peptides and inflammatory factors in the extracellular matrix.
1 citations
,
March 2022 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that HIF-P4H-2 function in FoxD1-lineage cells is crucial for normal hair follicle development and homeostasis in mice, implicating disrupted HIF, TGF-β, and Notch signaling pathways in associated defects.
30 citations
,
April 2017 in “Experimental Dermatology” This review explores the role of hair follicle dermal stem cells in skin regeneration and restorative therapies, but it reports no new experimental results.
January 2025 in “Open Life Sciences” This study observed that transgenic mice with overexpression of HE4 developed keratitis and severe corneal opacity, suggesting that HE4 may significantly influence keratopathy and inflammatory responses in the eye.
15 citations
,
January 2018 in “Journal of Cutaneous Medicine and Surgery” This case report presents a 6-year-old boy with both folliculotropic mycosis fungoides and primary follicular mucinosis, providing insights on differentiating the two conditions in pediatric patients.
8 citations
,
October 2023 in “Folia Histochemica et Cytobiologica” This study observed that exosomes from adipose mesenchymal stem cells overexpressing hepatocyte growth factor significantly improved liver function and reduced fibrosis in mice with experimentally induced liver injury.
41 citations
,
January 1992 in “Journal of medical genetics” This study described seven male patients and six female carriers of keratosis follicularis spinulosa decalvans, highlighting distinct dermatological and ophthalmic markers including follicular hyperkeratosis and corneal dystrophy.
1 citations
,
March 2020 in “Hair transplant forum international” This study describes new devices, "HairMeasure" and "Scalp Zone Identifier," which offer an economical method to calculate Hair Mass Index without disposable materials.
November 2025 in “Informatica” This study introduces a novel image enhancement method that significantly improves the visual quality of low-light sports images by utilizing improved bilateral filtering and the CLAHE algorithm, achieving a 65.24% improvement in color and edge detail preservation compared to state-of-the-art methods on the LOL dataset.