Remolding Microenvironmental Homeostasis for Enhancing Regenerative Hypertrophic Scar Treatment Based on Functionalized Microneedles
July 2025
in “
Interdisciplinary materials
”
hypertrophic scars functionalized microneedles mitophagy apoptosis inflammation curcumin-loaded extracellular vesicles decellularized extracellular matrix umbilical cord-derived mesenchymal stem cells M2 macrophage polarization collagen deposition hair follicle formation curcumin stem cells microneedle patch
Studysummary This study found that a microneedle patch integrating curcumin-loaded vesicles and a stem cell-derived matrix showed promise in reducing hypertrophic scars and promoting hair follicle formation in a rabbit model.
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