Remolding Microenvironmental Homeostasis for Enhancing Regenerative Hypertrophic Scar Treatment Based on Functionalized Microneedles

    July 2025 in “ Interdisciplinary materials ”
    Shengjie Jiang, Jialiang Zhou, Liyun Wang … Kaili Lin
    Studysummary This study found that a microneedle patch integrating curcumin-loaded vesicles and a stem cell-derived matrix showed promise in reducing hypertrophic scars and promoting hair follicle formation in a rabbit model.
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    Research cited in this study 3

    1. Local and Systemic Mechanisms That Control the Hair Follicle Stem Cell Niche Nature Reviews Molecular Cell Biology · 2023
    2. Going Below and Beyond the Surface: Microneedle Structure, Materials, Drugs, Fabrication, and Applications for Wound Healing and Tissue Regeneration Bioactive Materials · 2023
    3. Mechanical Stretch Induces Hair Regeneration Through the Alternative Activation of Macrophages Nature Communications · 2019