A Case of Cutaneous Focal Mucinosis With Follicular Induction

February 2017 in “ The American journal of dermatopathology/American journal of dermatopathology ”

Cem Leblebıcı

TLDR A man with a skin nodule was diagnosed with a rare skin condition called cutaneous focal mucinosis, which can be confused with other skin cancers.

The document describes a case of cutaneous focal mucinosis (CFM) with follicular induction in a 52-year-old man with type 2 diabetes, who presented with an asymptomatic reddish nodule on his abdominal skin. Histopathological examination revealed a polypoid lesion with mucin accumulation in the dermis, spindled cells, stellate fibroblasts, and immature hair follicle-like structures that resembled superficial basal cell carcinoma. The diagnosis of CFM with follicular induction of the epidermis was established. CFM is a rare condition characterized by localized dermal mucinosis and is clinically presented as a skin-colored papule or nodule. The etiopathogenesis of CFM is unclear, but it may be a reactive lesion potentially triggered by trauma. The case emphasizes the importance of recognizing follicular inductive changes overlying CFM to avoid misdiagnosis with conditions like superficial basal cell carcinoma or dermatofibroma with myxoid change.

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