105 citations,
October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.
29 citations,
May 2020 in “npj Regenerative Medicine” Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.
[object Object] 7 citations,
January 2016 in “Methods in molecular biology” Mouse hair follicle stem cells were successfully isolated and used to regenerate hair follicles with two different methods.
61 citations,
September 2008 in “Stem Cells” Most hair follicle stem cells do not protect their DNA by dividing it unevenly.
59 citations,
March 2020 in “Journal of Biomedical Science” Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.
47 citations,
April 2000 in “The American journal of pathology” Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.
21 citations,
November 2017 in “Scientific Reports” Different human hair follicle stem cells grow at different rates and respond differently to a baldness-related compound.
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November 2015 in “Trends in biotechnology” Gene regulation could revolutionize hair color by altering pigmentation from within.
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December 2020 in “Mammalian genome” Harlequin mutant mice have hair loss due to low AIF protein levels and retroviral element activity.
333 citations,
February 2010 in “Cell Stem Cell” Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.
242 citations,
February 2016 in “Science” Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.
211 citations,
May 2018 in “Trends in cell biology” Different types of skin cells play specific roles in development, healing, and cancer.
197 citations,
January 2019 in “Neuropsychopharmacology” Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.
145 citations,
November 2018 in “Nature Communications” The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
144 citations,
September 2012 in “Genes & development” Aging causes skin stem cells to work less effectively.
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August 2015 in “Experimental Dermatology” Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.
75 citations,
March 2014 in “Journal of Investigative Dermatology” Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.
60 citations,
October 2005 in “Experimental Dermatology” Zinc can both inhibit and stimulate mouse hair growth, and might help recover hair after chemotherapy.
52 citations,
October 2012 in “Journal of Dermatological Science” The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
47 citations,
February 2021 in “Pharmacological research” Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.
38 citations,
April 2016 in “Experimental Dermatology” The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.
32 citations,
August 2015 in “Journal of Investigative Dermatology” Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.
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July 2017 in “BioEssays” Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
24 citations,
December 2014 in “International Journal of Molecular Medicine” Eclipta alba extract helps increase hair growth and decrease hair loss-related protein in mice.
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June 2014 in “Journal of Pharmaceutical Sciences” Finasteride cream helps hair growth with less side effects.
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November 2008 in “Disease-a-Month” A common cause of skin infections in the U.S. is a strain of bacteria resistant to certain antibiotics, and prevention focuses on cleanliness and avoiding close contact.
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February 2019 in “Gene” Researchers found a good way to isolate hair follicle stem cells from newborn goats for further study.
14 citations,
December 2020 in “Journal of Investigative Dermatology” Aging causes changes in the scalp that can affect hair growth and lead to older-looking hair in women.
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January 2013 in “Postępy Dermatologii i Alergologii” The conclusion is that a combination of noninvasive treatments and lifestyle changes can improve skin health during menopause.
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March 2020 in “PloS one” α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.