13 citations
,
January 1997 in “Biochemical Pharmacology” This study found that human liver dehydroepiandrosterone sulfotransferase (DHEA ST) catalyzes the sulfate conjugation of minoxidil, indicating another pathway contributing to its metabolism in humans.
1 citations
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January 2018 in “Journal of Gynecologic Surgery” This article reports two cases where ovarian hyperthecosis caused hyperandrogenism in postmenopausal women, confirmed by imaging and resolved after bilateral oophorectomy.
30 citations
,
August 2005 in “British journal of dermatology/British journal of dermatology, Supplement” This study identified a novel CDH3 mutation associated with sparse hair and pigmentary macular changes in two siblings with hypotrichosis but no visual symptoms.
November 2009 in “Reactions Weekly” Two women lost hair after mesotherapy for hair loss, with one having permanent and the other temporary hair loss.
23 citations
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December 1977 in “Virchows Archiv B Cell Pathology” 1 citations
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January 2007 in “AIP conference proceedings” This study used phase contrast hard x-ray microscopy to capture detailed images of healthy human hair, revealing distinct structures such as the medulla, cortex, and cuticular layer.
15 citations
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May 2017 in “Journal of Cellular Biochemistry” This review discusses the role of the hairless protein (HR) in alopecia and cancer, noting its potential importance in cancer cell growth and survival, and reports no new experimental results.
24 citations
,
November 2013 in “Molecular Medicine Reports” This study demonstrated that human hair follicle stem cells can be efficiently differentiated into endothelial-like cells using VEGF and bFGF, suggesting their potential as a novel cell source for vascular tissue engineering.
10 citations
,
July 2016 in “Clinical and translational science” In this study, sorafenib's common adverse events, like a hand-foot syndrome and diarrhea, were observed in distinct temporal and tissue distribution patterns, revealing new relationships among effects.
August 2023 in “Asian journal of pharmaceutical and clinical research” This descriptive longitudinal study conducted in a Kolkata hospital found that intense pulsed light treatment significantly improved hirsutism in patients, as evaluated by trichoscopy and visual analog scores, demonstrating its effectiveness and safety for hair removal, independent of medical treatment.
April 2022 in “Our Dermatology Online” This case report details a 40-year-old woman with idiopathic hirsutism, as she exhibited terminal hair on the left side of her chin without signs of hyperandrogenism.
3 citations
,
October 1994 in “Journal of Dermatological Science” This study developed a novel monoclonal antibody, TYHF-1, which specifically reacts with hair keratins but not with epidermal keratins or various other tissue cells.
16 citations
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February 2019 in “Gene” This study describes two methods for isolating hair follicle stem cells from newborn Yangtze River Delta White Goats, highlighting differences in cell viability and marker protein expression between the methods.
January 1986 in “Journal of Steroid Biochemistry” Women with severe acne, hirsutism, and androgenic alopecia often have higher levels of certain androgens, but the specific pattern can't be predicted just by looking at symptoms.
3 citations
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September 2013 in “Journal of the American Academy of Dermatology” This report details two patients with Hutchinson-Gilford Progeria syndrome who exhibited generalized shiny skin in infancy and had a novel mutation in the LMNA gene.
212 citations
,
September 2015 in “Journal of Investigative Dermatology” This article presents a comprehensive guide for classifying human hair follicle cycle stages in vivo using scalp xenografts on immunocompromised mice, offering valuable resources for researchers in the field.
52 citations
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March 2011 in “Clinical Gastroenterology and Hepatology” This article reviews current therapies for exocrine pancreatic insufficiency in chronic pancreatitis, highlighting the challenges in achieving optimal enzyme dosing and the potential need for treatment even in asymptomatic patients.
September 2023 in “The Journal of Dermatology” In this study, injecting dermal sheath cup cells into affected areas of pattern hair loss improved hair thickness and patient-reported hair appearance in 62.9% of the participants, with better results in women, without serious side effects.
1 citations
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September 2019 in “Journal of Investigative Dermatology” This study found that combining human dermal papilla fibroblasts with hair matrix cells formed organoids capable of limited hair follicle development in ex vivo skin, but not fully formed hair follicles.
March 2024 in “Journal of drugs in dermatology” This study evaluated the safety and effectiveness of HASHA, a new hyaluronic acid injectable, for chin augmentation in adults with chin retrusion. HASHA significantly improved chin appearance and satisfaction over 12 months compared to controls, with only mild or moderate transient adverse events.
Hirsutism is relatively common among young Greek women.
This case study reports that prolonged high-dose vitamin A intake led to multiple adverse health effects in a young man, which mostly resolved after stopping the supplement, although liver changes persisted.
9 citations
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December 1987 in “European journal of endocrinology” In this study, 12 months of cyproterone acetate and ethinyl oestradiol treatment significantly reduced hair growth rate and certain hormone levels in hirsute women, though hair density and prolactin levels remained unchanged.
March 2018 in “Benha Journal of Applied Sciences” This study found that while prolactin and DHEA-S levels were higher in women with hirsutism compared to controls, there was no significant correlation between second to fourth digit ratio and hormonal profiles.
83 citations
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January 2023 in “Development” This review provides an overview of Hox genes, focusing on their evolutionary history, genomic organization, and roles in development, but reports no new study results.
December 2021 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found that knocking out the Hars2 gene in mouse cochlear hair cells led to mitochondrial dysfunction and ROS stress, resulting in progressive hearing loss and differential effects on inner and outer hair cells.
1 citations
,
April 2025 in “Journal of Cosmetic Dermatology” This study found that using Alastin Restorative Skin Complex Serum 2.0 with TriHex Technology for 12 weeks significantly improved facial skin hydration, elasticity, and overall quality in individuals with moderate to severe skin aging, with histological evidence showing new collagen and elastin fibers.
1 citations
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May 2022 in “International Journal of Pharmaceutical Sciences and Drug Research” This study reported that Hibiscus syriacus L. extracts, especially the ethanolic version, significantly reduced blood glucose and improved lipid profiles in diabetic rats, suggesting potential anti-diabetic benefits.
22 citations
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August 2011 in “Endocrine Practice” This review discusses the etiology, diagnosis, and management strategies for hirsutism, noting that serious underlying disorders are rare and emphasizing targeted treatment to manage testosterone's effects.
2 citations
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June 2004 in “Journal of Molecular Histology”