A Systemic-Like Disease: Chronic Vitamin A Poisoning

January 1986 in “ PubMed ”

Anne–Catherine Baglin, C Hagege, Brigitte Franc, M Richaud, J Prinseau

vitamin A poisoning hair loss skin dryness peeling liver enlargement ascites pleural effusion hypercalcemia acute renal failure liver fibrosis

TLDR Excessive vitamin A intake caused severe health issues that mostly resolved after stopping the intake.

A 22-year-old man ingested over 300 million I.U. of vitamin A over 2 years, leading to symptoms like diffuse arthralgia, weight loss, low-grade fever, skin dryness and peeling, hair loss, liver enlargement with ascites, and pleural effusion. Despite normal plasma levels of vitamin A and retinol-binding protein, he had raised E.S.R., hypercalcemia, and acute renal failure. Symptoms resolved after stopping vitamin A, except for liver enlargement. Biopsies showed high liver vitamin A levels, cortical bone thickening, and liver fibrosis development.

View this study on pubmed.ncbi.nlm.nih.gov →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community How did you get over the fear mongering of Fin/Dut?

in Finasteride/Dutasteride 62 upvotes 1 month ago

The conversation is about overcoming fear of finasteride/dutasteride for hair loss treatment. Users suggest starting with a small supply, noting side effects are rare and reversible, and emphasize personal comfort and confidence.

community Finally seeing a modest gain after over 1 year on fin and 3 months on minox. I actually have my part returning!

in Progress Pictures 808 upvotes 3 years ago

User sees modest hair gain after 1 year on finasteride and 3 months on minoxidil. Others offer support and share experiences with hair loss treatments.

community Is it me or are people losing their hair very young now?

in Finasteride/Dutasteride 143 upvotes 4 years ago

People notice more young individuals experiencing hair loss and discuss possible reasons, such as diet, hormones, and stress. Some treatments mentioned include finasteride, dutasteride, and minoxidil.

community Need help bros 2.5mg Dut/RU/min ISNT enough

in Finasteride/Dutasteride 1 month ago

A user is experiencing worsening hair loss despite using 2.5mg Dutasteride, RU58841, and Minoxidil daily for over 8 months. They are concerned that daily nicotine from vaping might be counteracting the treatments.

community The Golden Hair Regrowth/Loss Prevention Regimen With Results and Explanation

in Treatment 226 upvotes 2 years ago

Hair loss prevention and regrowth regimen includes finasteride, oral minoxidil, stemoxydine, hair growth serum, derma rolling, and ketocanazole shampoo. Users discuss efficacy, safety, and personal experiences with treatments.

community Went home for the holidays and my Dad asked ‘what have you done to your hair?’ he was genuinely happy for me and supportive when I told him I was growing it back with finasteride. AMA – 7 months in.

in Progress Pictures 534 upvotes 2 years ago

User experienced significant hair regrowth after 7 months of using 0.5mg finasteride, along with minoxidil and dermastamp. Side effects include increased sensitivity to poor lifestyle choices, but overall confidence improved.

Related Research

1 / 1 results

research A Systemic-Like Disease: Chronic Vitamin A Poisoning

January 1986 in “PubMed”

Excessive vitamin A intake caused severe health issues that mostly resolved after stopping the intake.