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The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Fungi-produced compounds can change plant root growth.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Hair loss needs more research for better treatments.

A man with vitiligo and alopecia saw quick skin and hair improvement with ruxolitinib, but skin color gains were lost after stopping treatment.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Microneedling is promising for treating various skin issues but needs more research to confirm its effectiveness and safety.

The Protein-Sparing Modified Fast is effective for rapid weight loss and maintaining it, but requires medical supervision and can have side effects.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Platelet-rich plasma might help tissue regeneration in dentistry, but results vary and more research is needed.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.

Hair grays due to oxidative stress and fewer functioning melanocytes.

Minoxidil and finasteride are effective for male hair loss, minoxidil for female hair loss, and various treatments like corticosteroids work for alopecia areata; treatment should be tailored to the individual.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

The hair follicle is a great model for research to improve hair growth treatments.

Doctors need to be better prepared to assess and treat obesity in patients.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Conductive hydrogels show promise for medical uses like healing wounds and tissue regeneration but need improvements in safety and stability.