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PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Growth factors are crucial for hair development and could help treat hair diseases.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Blue light promotes hair growth by interacting with specific receptors in hair follicles.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Korean Red Ginseng has beneficial components that help with stress, immunity, fatigue, memory, blood flow, and disease protection.

β-Catenin signaling is involved in brain cell growth after injury and could be a therapy target.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.

PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

Apoptosis is crucial for healthy skin and treating skin diseases.

RANK-RANKL signaling is essential for hair growth and skin health.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.