February 2025 in “Experimental Cell Research” In this laboratory study, the researchers found that combining dermal papilla cell-derived exosomes with collagenous sequences significantly enhanced hair follicle stem cell migration and proliferation, highlighting a potential strategy for hair regeneration through modulation of the hsa-novel-238a-CASP9 axis.
98 citations
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June 2001 in “Journal of biological chemistry/The Journal of biological chemistry” This study identified a cluster of genes on chromosome 17 related to hair keratin-associated proteins, including 37 genes forming seven multigene families, localized in the hair shaft's upper cortex.
22 citations
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June 2008 in “Experimental Dermatology” This study found that heparanase is primarily located in the inner root sheath of human hair follicles during the anagen phase, and inhibiting it in cultured hair follicles induces a catagen-like process.
14 citations
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January 1980 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” This study found that both cyproterone acetate alone and combined with ethinyl oestradiol reduced androgen levels and slightly increased SHBG binding in women with hirsutism, but showed no difference in hair regrowth rate between the treatments.
1 citations
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May 2024 in “Skin Appendage Disorders” This study describes trichoscopic findings in 11 dark-skinned women with central centrifugal cicatricial alopecia and highlights the potential of trichoscopy for early diagnosis and treatment.
The text is about acne, excessive hair growth, and hair loss due to hormones.
January 2025 in “International Journal of Reproduction Contraception Obstetrics and Gynecology” This hospital-based observational study of 300 women with hirsutism found that polycystic ovarian syndrome was the main cause of moderate hirsutism, with dietary habits and lifestyle factors, such as frequent consumption of meat, fried food, and alcohol, significantly associated with the condition.
1 citations
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January 2024 in “International Journal of Epidemiology” This study describes the ongoing HABIT study in Taicang, China, which aims to identify risk factors and the relationship between cardiovascular and neurodegenerative diseases among 10,357 adults, by collecting and analyzing long-term data on health, lifestyle, and biological specimens. Results are not yet available.
1 citations
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December 1978 in “British journal of dermatology/British journal of dermatology, Supplement” Hormonal imbalances in congenital adrenal hyperplasia cause acne.
18 citations
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January 2020 in “Journal of Clinical Research in Pediatric Endocrinology” This review discusses the pathophysiology, diagnosis, and management of functional hypothalamic amenorrhea in adolescent girls and reports no new clinical results.
13 citations
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January 2012 in “International Journal of Trichology” In this study, idiopathic hirsutism was identified as the most common cause of hirsutism among the participants, with a significant difference in hormone levels between cases of polycystic ovarian syndrome and idiopathic hirsutism.
December 1997 in “Journal of The European Academy of Dermatology and Venereology” In this study, hormonal abnormalities were detected in all investigated hirsute Saudi women, with elevated major androgens in 85.9% and polycystic ovaries in 59% of cases.
January 2013 in “Obstetrical & gynecological survey” This review discusses diagnostic and management approaches for hirsutism, emphasizing that most cases are due to polycystic ovary syndrome or obesity-related disorders, with idiopathic hirsutism often treated cosmetically.
May 2026 in “Research Square” In this study of women aged 18-45 from an endocrine referral group, researchers found that while clinical hirsutism severity is independently associated with biochemical hyperandrogenism, the relationship is modest and suggests different biological aspects are at play.
14 citations
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January 1980 in “Dermatology” In this study, oral cyproterone acetate reduced hair density and diameter in women with idiopathic hirsutism, but the effects were not permanent after stopping treatment, and plasma androgen levels remained unchanged.
January 2011 in “Revista Portuguesa de Endocrinologia Diabetes e Metabolismo” This article presents a case of congenital adrenal hyperplasia and myelolipoma in a 56-year-old woman, describing her symptoms and characteristics without offering new clinical results.
4 citations
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March 2012 in “Our Dermatology Online” This study conducted physical examinations on fifty women with hirsutism, focusing on virilization signs, but reports no new clinical findings.
September 2021 in “Psychoneuroendocrinology” This study observed that female nurses experienced higher hair cortisol concentrations, indicating increased stress, during periods of the COVID-19 pandemic compared to the summer release period.
December 2019 in “Case Medical Research” 5 citations
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April 2023 in “Life” This review discusses central centrifugal cicatricial alopecia in adolescents, noting varied presentation and highlighting genetic and environmental factors, but reports no new clinical findings.
November 2025 in “Journal of the European Academy of Dermatology and Venereology” In this study, single-cell RNA sequencing of hair follicle populations from hidradenitis suppurativa patients identified three endotypes, suggesting distinct epithelial-immune interactions that may guide stratified therapeutic approaches.
86 citations
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June 1998 in “Journal of Investigative Dermatology” This study found that mutations in the hairless gene in mice disrupt hair follicle integrity during catagen, leading to baldness due to disintegrating epithelial structures and loss of normal dermal papilla.
September 2009 in “Hair transplant forum international” This article reports that the ISHRS has formed a committee to register hair restoration outcomes in patients with cicatricial alopecia and other hair diseases, without presenting new research findings.
October 2024 in “InnovAiT Education and inspiration for general practice” In this article, the authors review the causes, diagnosis, and treatment approaches for hirsutism in women, emphasizing diagnosis, hormonal therapies, lifestyle modifications, and cosmetic options for managing this condition in primary care settings.
3 citations
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November 2005 in “Women's health” This narrative review discusses various causes and treatments of hirsutism in women, emphasizing the importance of identifying androgen-secreting tumors, but does not present new study results.
December 2023 in “Expert Review of Endocrinology & Metabolism” In this study, researchers described hyperandrogenism as a condition resulting from excessive androgen production, which can lead to symptoms like acne, hirsutism, and hair loss, particularly relevant for dermatological evaluation and management in adult females.
November 1968 in “Journal of the American Pharmaceutical Association”
January 2024 in “Indonesian Journal of Pharmaceutical Education” In this experimental laboratory study, three cream formulations containing 1% Caffeine Herbasome® were developed and evaluated for stability, homogeneity, pH, dispersion, and adhesion, with results showing satisfactory stability and suitable adhesion properties for skin application.
1 citations
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July 2021 in “Acta dermatovenerologica Croatica” This case report describes regression of hidradenitis suppurativa lesions in two patients after 16 weeks of adalimumab treatment.
2 citations
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October 2022 in “Frontiers in genetics” This case report describes a 46-year-old Italian woman with congenital adrenal hyperplasia who experienced significant improvements in physical and psychological health after receiving a delayed diagnosis and subsequent treatment.