Central Centrifugal Cicatricial Alopecia in Adolescents: Overview of Literature

Central Centrifugal Cicatricial Alopecia (CCCA) primarily affects women of African descent and is emerging in adolescents and Asian populations. The condition involves genetic and environmental factors, including hairstyling practices, and is linked to metabolic dysregulation, increasing risks for diabetes and breast cancer. A study of 6 adolescents with CCCA showed varied symptoms like scalp pruritus and patchy hair loss, suggesting an autosomal dominant inheritance pattern and dysregulated inflammatory pathways. Early diagnosis through biopsies is crucial. Management is challenging, requiring early intervention and therapies such as topical corticosteroids and behavioral modifications. The document emphasizes the need for further research to improve understanding and treatment strategies.