188 citations,
June 1998 in “Molecular cell” Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.
64 citations,
October 1998 in “Acta dermato-venereologica” Grape seed proanthocyanidins can promote hair growth.
56 citations,
September 2010 in “Veterinary pathology” Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.
53 citations,
July 2016 in “Cosmetics” Future hair cosmetics will be safer and more effective.
29 citations,
January 2017 in “Journal of Investigative Dermatology” The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.
26 citations,
January 2007 in “Organogenesis” Bioengineering can potentially treat hair loss by regenerating hair follicles and cloning hair, but the process is complex and needs more research.
13 citations,
April 2018 in “Scientific Reports” The genes KRT25 and SP6 affect curly hair in horses, with KRT25 also causing hair loss. If both genes are mutated, the horse gets curly hair and hair loss. KRT25 can hide the effect of SP6.
5 citations,
February 2022 in “Acta Biomaterialia” Nanomaterials can improve hair care products and treatments, including hair loss and alopecia, by enhancing stability and safety, and allowing controlled release of compounds, but their safety in cosmetics needs more understanding.
36 citations,
November 2019 in “Molecular biology and evolution” Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.
3 citations,
April 1990 in “Archives of dermatology” The book reveals diverse patterns of hair growth in different species and advancements in hair and alopecia research.
Hair keratin treatments can be harmful, potentially causing health issues like skin reactions and cancer.
40 citations,
July 2015 in “Journal of Cellular Biochemistry” Cysteine helps maintain keratin production in skin cells even when iron is low.
Keratin hydrogels from human hair show promise for tissue engineering and regenerative medicine.
98 citations,
May 2016 in “Genes” Understanding wool keratin-associated proteins in sheep can help improve wool quality through selective breeding.
24 citations,
November 2015 in “Scientific reports” Human hair has a new region with ordered filaments and the cuticle contains β-keratin sheets.
11 citations,
April 2022 in “Biophysical Journal” Disulfide bonds in keratin fibers break more easily under stress, especially when wet, affecting fiber strength.
8 citations,
March 2004 in “Mammalian genome” KAP genes are crucial for hair development and show both shared and unique traits in humans, chimpanzees, and baboons.
6 citations,
January 2022 in “Gene” Scientists found 53 keratin genes in yaks that are important for hair growth and share similarities with those in other animals.
20 citations,
June 2012 in “British Journal of Dermatology” Bleaching hair damages protein structure, especially keratin, leading to weakened hair.
10 citations,
November 2021 in “International journal of molecular sciences” Sheep and goat hair fibers are complex due to keratin-associated proteins, which are important for fiber properties and growth.
7 citations,
July 2019 in “Animals” The KRTAP21-1 gene affects wool yield and can help improve wool production.
4 citations,
January 2020 in “Genes” The KRTAP21-2 gene affects wool length and quality in sheep.
3 citations,
December 2021 in “Materials today communications” A new film made from human hair supports skin cell growth better than collagen.
1 citations,
September 2023 in “Animals” A new goat gene affects cashmere fiber thickness; certain variations can make the fibers coarser.
The KRTAP36-2 gene in sheep affects wool yield.
February 2023 in “European biophysics journal” 23 citations,
November 2001 in “Archives of Dermatology” Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.
13 citations,
March 2019 in “Journal of cosmetic dermatology” Heat damages hair, with Asian hair losing more protein than Caucasian hair.
10 citations,
May 2020 in “Journal of proteome research” Explosions don't stop hair proteins from being used to identify people.
25 citations,
September 2014 in “SpringerPlus” Sheep have a unique gene, KAP8-2, that humans don't have, which may affect wool properties.