Identification of the Keratin-Associated Protein 22-2 Gene in Capra Hircus and Its Association with Cashmere Traits

    September 2023 in “ Animals ”
    Zhanzhao Chen, Jian Cao, Fangfang Zhao, Zhaohua He, Hongxian Sun, Jiqing Wang, Xiu Liu, Shaobin Li
    TLDR A new goat gene affects cashmere fiber thickness; certain variations can make the fibers coarser.
    The study involved 356 Longdong Cashmere goats and identified a new gene, Keratin-Associated Protein 22-2 (KRTAP22-2), in goats. This gene was found to significantly influence the diameter of cashmere fibers. Four single nucleotide polymorphism sites (SNPs) were detected in the KRTAP22-2 gene, and a specific variation, allele B, was associated with a 2.2% increase in mean fiber diameter. The presence of allele B could lead to the production of coarser cashmere fibers, suggesting that selecting goats without this allele could result in finer cashmere. The study also found that a mutation in the coding region of the KRTAP22-2 gene may affect the structure or expression of the KAP22-2 protein, thereby influencing the average fiber diameter trait of cashmere. This new gene could play a significant role in goat breeding programs aimed at reducing cashmere fiber diameter.
    Discuss this study in the Community →

    Research cited in this study

    11 / 11 results

    Related Community Posts Join

    6 / 101 results

      community Keratin microspheres - breakthrough

      in Research/Science  13 upvotes 8 months ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community Comprehensive Microneedling Guide

      in Microneedling  295 upvotes 2 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

      community Results of Procyanidin B2 in clinical studies

      in Treatment  13 upvotes 4 years ago
      Procyanidin B2, a compound derived from Annurca apples, as a potential treatment for pattern hair loss. Several clinical studies were mentioned, which found that procyanidin B2 could increase hair growth, density, and keratin content. Other treatments such as Minoxidil, Finasteride, and RU58841 were not discussed.

      community Female Hair Loss, Is there anything else I should be doing?

       11 upvotes 10 years ago
      A 20-year old female experiencing hair loss, who has had normal blood tests and is currently using minoxidil as recommended by her doctor. She is asking if there are any other treatments she should consider.

      community Keratin fibers vs. Gossypium Herbaceum Hair fibers

      in Product  1 upvotes 2 months ago
      The conversation is about comparing keratin hair fibers to Gossypium Herbaceum hair fibers for diffuse hair loss. The user prefers keratin fibers for their durability and is seeking a bulk purchase option.

    Similar Research

    5 / 1000+ results