research Cellular Therapeutics and Immunotherapies in Wound Healing – On the Pulse of Time?
Cellular and immunotherapies show promise for healing chronic wounds but need more research.
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930-960 / 1000+ results research The Evolutionary Impact of Androgen Levels on Prostate Cancer in a Multi-Scale Mathematical Model
Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
research Transcriptome Meta-Analysis Confirms the Hidradenitis Suppurativa Pathogenic Triad: Upregulated Inflammation, Altered Epithelial Organization, and Dysregulated Metabolic Signaling
The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.
research Maintenance of Barrier Tissue Integrity by Unconventional Lymphocytes
Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.
research Cell Surface B2m-Free Human Leukocyte Antigen Monomers and Dimers: Are They Neo-HLA Class and Proto-HLA?
B2m-free HLA variants may be a new class of HLA important in immune responses and diseases.
research Resident Macrophages of the Lung and Liver: The Guardians of Our Tissues
Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.
research PRC2 Preserves Intestinal Progenitors and Restricts Secretory Lineage Commitment
PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.
research Intestinal Intraepithelial Lymphocytes: Sentinels of the Mucosal Barrier
Intestinal intraepithelial lymphocytes are crucial for gut immunity and maintaining the mucosal barrier.
research Fibroblasts: Immunomodulatory Factors in Refractory Diabetic Wound Healing
Fibroblasts are important in healing diabetic wounds, but high sugar levels can harm their function and slow down the healing process.
research Update on Melasma—Part I: Pathogenesis
Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
research Oral Lichen Planus: A Chronic Systemic Disease with Immune-Mediated Pathogenesis
Oral lichen planus is a chronic disease causing mouth discomfort and sometimes needs immunosuppressive treatment.
research Mutations in the Vitamin D Receptor and Hereditary Vitamin D-Resistant Rickets
Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.
research Chronic Administration of Minoxidil Protects Elastic Fibers and Stimulates Their Neosynthesis with Improvement of the Aorta Mechanics in Mice
Minoxidil helps protect and rebuild elastic fibers in arteries, improving artery function, especially in older females.
research Acne Protection: Measures and Miseries
Acne can be managed with various treatments and requires psychological support due to its emotional impact.
research Sp6 Downregulation of Follistatin Gene Expression in Ameloblasts
Sp6 promotes tooth development by reducing follistatin levels.
research Expression and Function of Keratinocyte Growth Factor and Activin in Skin Morphogenesis and Cutaneous Wound Repair
KGF and activin are crucial for skin healing and repair.
research Acne and Systemic Disease
Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.
research MicroRNA in Skin Diseases
Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.
research Hormone Therapy in Acne
Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.
research Improving Selective Androgen Receptor Modulator Discovery and Preclinical Evaluation
We need better ways to test and understand SARMs to make safer and more effective treatments.
research Dermatological Drugs and Cosmetics: Allergenic and Adverse Effects
Some cosmetics and dermatological drugs can cause allergic reactions and side effects, like skin irritation and systemic issues.
research The Endocannabinoid System of the Skin: A Potential Approach for the Treatment of Skin Disorders
Targeting the skin's endocannabinoid system could help treat skin disorders.
research Cutaneous Lupus Erythematosus: A Comprehensive Review
The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.
research The Emerging Role of Janus Kinase Inhibitors in the Treatment of Autoimmune and Inflammatory Diseases
Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.
research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne
Anti-acne medications may work by reducing the activity of a protein involved in acne development.
research The Paradox of p53: What, How, and Why?
The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
research Psychological Interventions in the Management of Common Skin Conditions
Using psychological treatments can help manage skin conditions along with regular medical care.
research Understanding the Role of Prostaglandin E2 in Regulating Human Platelet Activity in Health and Disease
Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.
research Diagnostic Approach to Low-Renin Hypertension
Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.
research New Pharmaceutical Concepts for Sebaceous Gland Diseases: Implementing Today's Pre-Clinical Data into Tomorrow's Daily Clinical Practice
New treatments for skin conditions related to the sebaceous gland are being developed based on current research.