Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
November 2023 in “Computational and Structural Biotechnology Journal” A single robotic system can accurately harvest and implant hair grafts, showing promise for real-world use.
September 2022 in “Scientific Reports” Scalp melanoma is more common and easier to diagnose early in people with androgenetic alopecia due to sun damage.
1533 citations,
October 2008 in “Endocrine reviews” Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
949 citations,
January 2001 in “Cell” Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.
245 citations,
October 2015 in “Nature medicine” Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.
234 citations,
November 2009 in “American journal of human genetics” Common variants in the Trichohyalin gene are linked to straight hair in Europeans.
63 citations,
April 2005 in “Mechanisms of development” Mice with too much Claudin-6 have skin barrier problems and abnormal hair growth.
34 citations,
August 2005 in “Dermatologic Clinics” Stress and emotional factors can worsen skin conditions by affecting the immune system.
27 citations,
January 2015 in “International Journal of Trichology” The supplement helps improve hair growth and reduce hair shedding.
25 citations,
April 2021 in “The EMBO Journal” Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
22 citations,
November 2016 in “International journal of molecular sciences” Vitamin D receptor is important for regulating hair growth and wound healing in mice.
11 citations,
February 2019 in “Stem cells international” Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.
6 citations,
October 2022 in “Frontiers in Cell and Developmental Biology” Transplanted hair follicle stem cells can heal damaged rat intestines.
5 citations,
May 2022 in “Biomedicines” Botryococcus terribilis and its compounds may promote hair growth and improve hair health.
3 citations,
July 2023 in “Frontiers in Aging” Hair follicle stem cells change states with age, affecting hair growth and aging.
2 citations,
June 2022 in “Cells” 3D cell cultures are better for testing hair growth treatments than 2D cultures.
2 citations,
May 2021 in “International journal of molecular sciences” Stem cells from hair follicles in a special gel show strong potential for bone regeneration.
1 citations,
January 2023 in “Science Advances” The skin's microbiome helps hair regrow by boosting certain cell signals and metabolism.
1 citations,
January 2021 in “Processes” Researchers successfully grew horse skin cells that produce pigment from hair follicle samples.
1 citations,
July 2020 in “International journal of radiology & radiation therapy” Partial hair-sparing brain radiotherapy is possible and doesn't affect cancer control but still causes noticeable hair loss.
January 2024 in “ACS Biomaterials Science & Engineering” A new method using a microfluidic device can prepare hair follicle germs efficiently for potential use in hair loss treatments.
September 2023 in “medRxiv (Cold Spring Harbor Laboratory)” Long-COVID has diverse, long-term health impacts, especially in young people.
July 2015 in “Cambridge University Press eBooks” The document concludes that careful history and physical exams are crucial for accurately diagnosing polycystic ovary syndrome and distinguishing it from other similar conditions.
8 citations,
October 2022 in “Regenerative Therapy” New regenerative treatments for hair loss show promise but need more research for confirmation.
80 citations,
September 2007 in “Cell Cycle” The study investigated the neural potential of stem cells in the bulge region of hair follicles using nestin-GFP mice. These cells demonstrated multipotency, capable of differentiating into various cell types, including neuronal, astrocytic, and oligodendrocytic cells, both in vitro and in vivo. Transcriptional profiling revealed a unique gene expression signature, indicating a distinct population of multipotent stem cells with broad differentiation potential. The research showed that these cells could form "hairspheres" and differentiate into neurons, astrocytes, smooth muscle-like cells, and keratinocytes under specific conditions. In vivo experiments confirmed their neural potential by successful differentiation into neuronal cells upon transplantation into chick embryos. The findings highlighted the plasticity of adult tissue-specific stem cells, challenging previous notions about their limited differentiation capabilities and suggesting their potential to contribute to both ectodermal and mesodermal lineages.
56 citations,
April 2019 in “The Plant Journal” Cyclic nucleotide-gated channels are crucial for proper root hair growth and calcium balance in plants.
214 citations,
April 2017 in “Cell” Different small areas within hair follicles send specific signals that control what type of cells stem cells become.
May 2022 in “Liver transplantation” The document explains how the immune system reacts to organ transplants and the treatments used to prevent rejection.
3 citations,
October 2023 in “Military Medical Research/Military medical research” Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.