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A man with severe hair loss saw hair and nail improvement after 10 months on tofacitinib without side effects.

Genetic mutations that disrupt homocysteine breakdown lead to increased damage in mouse hair keratin.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Bariatric surgery affects skin health, causing both direct complications and changes in existing skin conditions, often related to nutritional deficiencies.

Cantu syndrome, which causes excessive hair growth and skin issues, is due to a mutation in the ABCC9 gene, and understanding this could help develop new treatments for hair diseases.

The document concludes that immune system abnormalities cause alopecia areata, but the exact process is still not completely understood.

Two specific SNPs in the TRPS1 gene cause excessive hair growth by altering the protein's structure.

A rare ITGB6 gene variant causes intellectual disability, hair loss, and dental issues.

Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.

Early diagnosis and tailored treatments are crucial for managing ichthyosis syndromes with hair abnormalities.

Loose anagen hair syndrome is caused by structural abnormalities in the hair follicle's inner root sheath.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Understanding skin structure and development helps diagnose and treat skin disorders.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

KF19418 promotes hair growth similarly to minoxidil but is not better in live mice.

Applying a special compound can promote hair growth without harmful side effects.

Mice with human skin protein K8 had more skin problems and cancer.

Hormones, nutrition, and seasonal changes regulate hair growth cycles, with androgens extending growth phases and factors like aging and malnutrition affecting hair loss and thinning.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

Obese mice with a leptin gene mutation have a longer resting phase in their hair cycle, which may help understand certain hair loss conditions.

Hair shaft dysplasias are abnormal hair conditions that can be inherited or acquired and may signal other health issues, with limited treatment options available.

pCLCA2 protein may help maintain skin structure and function.

Androgens can both increase body hair and cause scalp hair loss.

Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.

Ring Chromosome 11 may be linked to conditions like early puberty, excessive hair growth, hair loss, and type 2 diabetes.

Defective mink guard hairs have split tips and missing cuticle cells, causing a metallic sheen.

Some hair loss disorders are caused by genetic mutations affecting hair growth.

The document concludes that understanding hair biology is key to treating hair disorders, with gene therapy showing potential as a future treatment.

Abnormal cuticle and hair shaft medulla cause hair loss in androgenetic alopecia; sonography helps diagnose and manage it.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.